85063-53-2

Basic information

• Product Name: N-(4-chlorophenyl)-6-methylbenzo[d]thiazol-2-amine
• Synonyms: N-(4-chlorophenyl)-6-methylbenzo[d]thiazol-2-amine
• CAS NO: 85063-53-2
• Molecular Weight: 274.774
• Mol File: 85063-53-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: N-(4-chlorophenyl)-6-methylbenzo[d]thiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorophenyl)-6-methylbenzo[d]thiazol-2-amine(85063-53-2)
• EPA Substance Registry System: N-(4-chlorophenyl)-6-methylbenzo[d]thiazol-2-amine(85063-53-2)

Safety Data

• Hazardous Substances Data: 85063-53-2(Hazardous Substances Data)

Upstream product

• 2536-91-6 6-methylbenzothiazol-2-ylamine 
• 106-47-8 4-chloro-aniline 
• 1642135-44-1 C₁₄H₁₀ClIN₂ 
• 583-68-6 2-bromo-p-toluidine 
• 2131-55-7 4-Chlorophenyl isothiocyanate 
• 29289-13-2 2-iodo-4-methylaniline 
• 14731-25-0 5-(4-methyl-anilino)-3H-[1,3,4]thiadiazole-2-thione 
• 74322-42-2 N-p-Tolyl-N'-p-chlorophenyl thiourea 
• 1397746-42-7 C₁₄H₁₂ClIN₂S 

Relevant articles and documents

[...] - anilino - [...] - [...]

The present invention discloses a novel 2-anilino-6-methylbenzothiazole derivative having the chemical formula (I), or a pharmaceutically acceptable salt, wherein the definition of each substituent is defined in the patent description and claims. This invention also discloses a method for preparing these derivatives as well as preparation of pharmaceutical chemicals for applications in treating hepatitis C.

Copper/N,N,N',N'-tetramethylethylenediamine-catalyzed synthesis of N-substituted benzoheterocycles via C-S cross-coupling at ambient temperature in water

Copper/N,N,N',N'-tetramethylethylenediamine (Cu/TMEDA)-catalyzed ambient temperature tandem reactions of isothiocyanates with 2-iodophenols or 2-iodoanilines in water without the protection of an inert atmosphere are described, which provide a simple, rapid, environmental method for the synthesis of a variety of 2-iminobenzo-1, 3- oxathioles and 2-aminobenzothiazoles in good yields. More important, the present reaction process needs only low amounts of copper catalyst (1mol%) and can yield the products on a gram scale.

1,10-Phenanthroline-catalyzed tandem reaction of 2-iodoanilines with isothiocyanates in water

The 1,10-phenanthroline-catalyzed tandem reaction of 2-iodoaniline with isothiocyanate in water is described, which provides an environmentally benign, efficient and simple route for the preparation of 2-aminobenzothiazoles. The present tandem process shows broad substrate scope in the absence of transition metals and phase-transfer catalysts. Copyright