85068-34-4

Basic information

• Product Name: 3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE
• Synonyms: 3',5'-Bis(trifluoromethyl)propiophenone98%;3',5'-Bistrifluoromethylpropiophenonehenone;1-(3,5-Bis(trifluoroMethyl)phenyl)propan-1-one;3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE;3,5-BIS(TRIFLUOROMETHYL)PROPIOPHENONE;3,5-DI(TRIFLUOROMETHYL)PROPIOPHENONE;TIMTEC-BB SBB005962;1-[3,5-Bis(trifluoromethyl)phenyl]-1-propanone
• CAS NO: 85068-34-4
• Molecular Formula: C₁₁H₈F₆O
• Molecular Weight: 270.17
• EINECS: 285-296-1
• Mol File: 85068-34-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 72°C 7mm
• Flash Point: 169 °F
• Appearance: /
• Density: 1.379 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.705mmHg at 25°C
• Refractive Index: n20/D 1.4245(lit.)
• Storage Temp.: 2-8°C
• BRN: 7484754
• CAS DataBase Reference: 3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE(85068-34-4)
• EPA Substance Registry System: 3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE(85068-34-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 85068-34-4(Hazardous Substances Data)

Usage

General Description

3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE is a chemical compound with the molecular formula C11H7F6O. It is a propiophenone derivative containing two trifluoromethyl groups, making it highly fluorinated. 3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE is often used as a building block in organic synthesis and pharmaceutical research due to its unique chemical properties. Its high level of fluorination makes it particularly useful in the development of fluorinated pharmaceuticals and agrochemicals. Additionally, the presence of the propiophenone moiety allows for various functionalization and modification reactions, increasing its versatility as a chemical building block in synthetic chemistry.

InChI:InChI=1/C11H8F6O/c1-2-9(18)6-3-7(10(12,13)14)5-8(4-6)11(15,16)17/h3-5H,2H2,1H3

Upstream product

• 401-95-6 3,5-Bis(trifluoromethyl)benzaldehyde 
• 184888-50-4 1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol 

Downstream Products

• 184888-50-4 1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol 
• 1491168-98-9 N-(1-(3,5-bis(trifluoromethyl)phenyl)propyl)-N-((4-phenylpyridin-3-yl)methyl)furan-2-carboxamide 
• 1453069-77-6 C₁₂H₁₃F₆N 
• 1359871-77-4 (2-amino-4-(3,5-bis(trifluoromethyl)phenyl)-5-methylthiophen-3-yl)(4-chlorophenyl)methanone 
• 1359871-80-9 (2-amino-4-(3,5-bis(trifluoromethyl)phenyl)-5-methylthiophen-3-yl)(4-tolyl)methanone 
• 1359871-76-3 (2-amino-4-(3,5-bis(trifluoromethyl)phenyl)-5-methylthiophen-3-yl)(phenyl)methanone 
• 1359871-78-5 (2-amino-4-(3,5-bis(trifluoromethyl)phenyl)-5-methylthiophen-3-yl)(3,4-dichlorophenyl)methanone 
• 1359871-79-6 (2-amino-4-(3,5-bis(trifluoromethyl)phenyl)-5-methylthiophen-3-yl)(3-(trifluoromethyl)phenyl)methanone 
• 863976-10-7 DL-ethyl-3-hydroxy-3-[3',5'-bis(trifluoromethyl)phenyl]pentanoate 
• 620950-09-6 DL-2-hydroxy-2-[3',5'-bis(trifluoromethyl)phenyl]butyramide 
• 685503-45-1 1-[3,5-bis(trifluoromethyl)phenyl]propylamine 

Relevant articles and documents

Thiourea inhibitors of herpes viruses. Part 2: N-Benzyl-N′- arylthiourea inhibitors of CMV

A series of highly potent thiourea inhibitors of cytomegalovirus (CMV) with improved stability properties was prepared and evaluated. Compound 29 inhibited the virus in cultured HFF cells with IC50 of 0.2nM.