85070-63-9Relevant academic research and scientific papers
2,2-Dichloroalkanecarboxylic acids, processes for their production and pharmaceutical agents containing these
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, (2008/06/13)
Pharmaceutical agents for treating diabetus mellitus which contain a compound of formula I STR1 as the active substance, in which A, B, A' and W have the meanings stated in the claims, new compounds of formula I as well as processes for their production.
ω-Substituted alkyl carboxylic acids as antidiabetic and lipid-lowering agents
Meyer, Kirstin,Voss, Edgar,Neidlein, Richard,Kuehnle, Hans-Frieder,Pill, Johannes
, p. 775 - 787 (2007/10/03)
In screening experiments certain ω-substituted alkyl carboxylic acids were found to produce an increase in insulin-stimulated 14C-acetate incorporation into triglycerides, which may indicate an improvement in the action of insulin. Antidiabetic
Synthesis of 3- and 4-(ω-Phenylalkyl)catechols, the Sap Exuded from a Burmese Lac Tree, Melanorrhoea Usitate
Miyakoshi, Tetsuo,Du, Yumin,Kumanotani, Ju
, p. 1054 - 1056 (2007/10/02)
The presence of 3- and 4-(ω-phenylalkyl)catechols in Burmese lac has been confirmed by their synthesis. 3-(ω-Phenylalkyl)veratroles were synthesized by alkylation of ω-phenylalkyl bromide with aryl lithium derived from veratrole. 4-(ω-phenylalkyl)veratroles were similarly obtained from w-phenylalkyl bromide and 4-bromoveratrole.Demethylation of 3- and 4-(ω-phenylalkyl)veratroles with boron tribromide gave the corresponding catechols in good yields.
Methode de synthese d'acides gras marques substitues ou non en α et en β
Apparu, Marcel,Comet, Michel,Leo, Pierre M.,Mathieu, Jean-Paul,Du Moulinet, Amaury,et al.
, p. 118 - 124 (2007/10/02)
2-Propyn-1-ol and the dibromides Br(CH2)nBr (n = 10-12) have been used as starting materials for the synthesis of α- and β-methyl-branched fatty acids (C16) labeled with 123I at the ω-position.The methyl groups are introduced through the use of the lithium salt of either propanoic or isobutyric acid.The synthesis of *IC6H5(CH2)14COOH and *IC6H5(CH2)12CH(CH3)CH2COOH have been achieved in the same way starting from phenylacetylene.In each case, the radioactive iodine atom is introduced by an I/*I exchange reaction.
