85079-48-7 Usage
Uses
Used in Pharmaceutical Industry:
TOXIN T-17 is used as a research tool for understanding the mechanisms of voltage-dependent Na+ channels and their role in nerve and muscle function. Its unique binding properties make it valuable in studying the effects of channel activators and blockers on these channels.
Used in Environmental Monitoring:
TOXIN T-17 is used as an indicator of the presence of harmful algal blooms, particularly red tide events caused by Ptychodiscus brevis. Monitoring the levels of this toxin can help assess the risk of toxic effects on marine life and humans exposed to contaminated water sources.
Used in Toxicology Research:
TOXIN T-17 is used as a model compound to study the toxic effects of marine toxins on various organisms, including humans. This research can contribute to the development of treatments and countermeasures for exposure to harmful algal blooms and their associated toxins.
Biochem/physiol Actions
Primary TargetVoltage-dependent Na+ channel activator
Safety Profile
A poison by ingestion,
intraperitoneal, and intravenous routes.
When heated to decomposition it emits
acrid smoke and irritating vapors.
Check Digit Verification of cas no
The CAS Registry Mumber 85079-48-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,0,7 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85079-48:
(7*8)+(6*5)+(5*0)+(4*7)+(3*9)+(2*4)+(1*8)=157
157 % 10 = 7
So 85079-48-7 is a valid CAS Registry Number.
InChI:InChI=1/C49H72O14/c1-24(23-50)13-27-16-38(51)49(7)42(53-27)18-33-34(61-49)17-32-28(54-33)9-8-10-29-36(56-32)22-48(6)41(57-29)20-40-46(4,63-48)12-11-30-44(60-40)25(2)14-31-37(55-30)21-47(5)39(58-31)19-35-45(62-47)26(3)15-43(52)59-35/h15,25,27-42,44-45,50-51H,1,8-14,16-23H2,2-7H3/t25-,27-,28-,29+,30+,31+,32+,33+,34-,35+,36-,37-,38+,39-,40+,41-,42-,44-,45-,46-,47+,48+,49+/m1/s1
85079-48-7Relevant academic research and scientific papers
Total synthesis of brevetoxin B
Kadota, Isao,Takamura, Hiroyoshi,Nishii, Hiroki,Yamamoto, Yoshinori
, p. 9246 - 9250 (2007/10/03)
The convergent total synthesis of brevetoxin B (1) has been achieved. The intramolecular allylation of the O,S-acetal 20, prepared from the α-chlorosulfide 17 and the alcohol 5, was carried out using AgOTf as a Lewis acid to give the diene 21, predominant
Synthesis of a multifunctional radioiodinatable photoaffinity probe
Mende,Schulman,Baden
, p. 5307 - 5310 (2007/10/02)
Synthesis is described which results in an iodinatable photoaffinity probe and derivatives which are useful in the covalent coupling of the probe to amine, carboxylic acid, and alcoholic hydroxy function on specific ligands of biological importance. Speci
