2-Trifluoromethyl-diphenhydramin, also known as 2-(trifluoromethyl)phenhydramine, is a chemical compound with the molecular formula C8H10F3N. It is a derivative of diphenhydramine, a well-known antihistamine used to treat allergies and as a sleep aid. The addition of a trifluoromethyl group (CF3) to the diphenhydramine structure enhances its lipophilicity, potentially improving its ability to cross cell membranes and interact with target receptors. This modification may also alter the compound's pharmacokinetics and pharmacodynamics, leading to different therapeutic effects or side effects compared to the parent compound. 2-Trifluoromethyl-diphenhydramin is a synthetic compound that may be used in pharmaceutical research to explore the effects of structural modifications on drug activity and safety.
The CAS Registry Mumber 851-66-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,5 and 1 respectively; the second part has 2 digits, 6 and 6 respectively. Calculate Digit Verification of CAS Registry Number 851-66: (5*8)+(4*5)+(3*1)+(2*6)+(1*6)=81 81 % 10 = 1 So 851-66-1 is a valid CAS Registry Number.