851069-56-2

Upstream product

• 851069-55-1 2-[1-ethoxy-meth-(E,Z)-ylidene]-5-methoxy-3-oxo-pentanoic acid ethyl ester 
• 38980-96-0 4-(trifluoromethyl)benzimidamide hydrochloride 

Downstream Products

• 851069-57-3 [4-(2-methoxy-ethyl)-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-methanol 

Relevant academic research and scientific papers

Indolyl and dihydroindolyl derivatives, their manufacture and use as pharmaceutical agents

This invention relates to compounds of the formula wherein one of R6, R7 and R8 is and X, Y1 to Y4, R1 to R14 and n are as defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.