851136-41-9

Upstream product

• 851136-38-4 methyl (R)-N-benzoyl-4-methoxyphenylglycinate 
• 851136-39-5 (R)-N-[2-hydroxy-1-(4-methoxyphenyl)ethyl]benzamide 
• 151-50-8 potassium cyanide 
• 851136-37-3 (R)-N-(1-(4-methoxyphenyl)-2-oxoethyl)benzamide 

Downstream Products

• 851136-42-0 (4R,5R)-2-phenyl-4-(4-methoxyphenyl)-1,3-oxazoline-5-carbonitrile 
• 691410-76-1 methyl (4R,5R)-4-(4-methoxyphenyl)-1,3-oxazolidine-2-one-5-carboxylate 
• 691410-81-8 methyl (4S,5S)-4-(4-methoxyphenyl)-1,3-oxazolidine-2-one-5-carboxylate 
• 691410-75-0 (4R,5R)-4-(4-methoxyphenyl)-1,3-oxazolidine-2-one-5-carboxylic acid 
• 220736-25-4 (4R,5S)-5-(hydroxymethyl)-4-(4-methoxyphenyl)-1,3-oxazolidin-2-one 
• 220736-25-4 (4R,5R)-cytoxazone 

Relevant academic research and scientific papers

Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach

Immunomodulator (-)-cytoxazone and its epimer (+)-epi-cytoxazone were synthesized starting from (D)-(-)-4-hydroxyphenylglycine. Homologation of the amino acid was achieved via the corresponding aldehyde, by a cyanohydrin reaction. The racemization of high