85117-88-0

Usage

Uses

Used in Pharmaceutical Research:
N-(4-acetyl-2-fluorophenyl)acetamide is used as a building block or intermediate for the synthesis of potential anti-tumor and anti-inflammatory agents. Its specific applications include its use in the development of new drugs for the treatment of cancer and inflammatory conditions.
Used in Agrochemical Production:
N-(4-acetyl-2-fluorophenyl)acetamide is also used as a building block or intermediate in the production of various agrochemicals, contributing to the development of new pesticides and other agricultural chemicals.
Used in Drug Discovery and Development:
The presence of the acetyl and fluoro groups in the structure of N-(4-acetyl-2-fluorophenyl)acetamide may contribute to its bioactivity and medicinal properties, making it a relevant target for drug discovery and development. Researchers can explore its potential as a lead compound for the creation of new therapeutic agents.

InChI:InChI=1/C10H10FNO2/c1-6(13)8-3-4-10(9(11)5-8)12-7(2)14/h3-5H,1-2H3,(H,12,14)

Upstream product

• 29632-74-4 2-fluro-4-iodoaniline 
• 75-16-1 methylmagnesium bromide 
• 97760-95-7 4-acetylamino-3-fluoro-benzaldehyde 
• 93129-68-1 4-acetylamino-3-fluoro-benzonitrile 
• 97760-94-6 N-(2-fluoro-4-iodo-phenyl)-acetamide 
• 348-54-9 2-Fluoroaniline 

Downstream Products

• 73792-22-0 1-(4-amino-3-fluorophenyl)ethanone 
• 97776-40-4 1-(4-Amino-3-fluoro-phenyl)-2-ethylamino-ethanol 
• 56795-45-0 4'-amino-3'-cyano-5'-fluoro-acetophenone 
• 54238-83-4 1-(4-Amino-3-chloro-5-fluoro-phenyl)-2-ethylamino-ethanone 
• 740030-01-7 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-ethylamino-ethanone 
• 56340-17-1 4'-amino-2-tert-butylamino-3'-fluoro-5'-iodo-acetophenone 
• 783246-62-8 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-(1,1-dimethyl-propylamino)-ethanone 
• 97776-43-7 1-(4-Amino-3-chloro-5-fluoro-phenyl)-2-ethylamino-ethanol 
• 97776-45-9 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-ethylamino-ethanol 
• 95656-56-7 1-(4'-Amino-3'-fluoro-5'-iodo-phenyl)-2-tert-butylamino-ethanol 
• 97776-50-6 1-(4'-Amino-3'-bromo-5'-fluoro-phenyl)-2-tert-pentylamino-ethanol 
• 54240-25-4 4'-amino-3'-bromo-2-cyclopropylamino-5'-fluoro-acetophenone 
• 745725-51-3 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone 
• 56340-21-7 2-Amino-5-(2-ethylamino-acetyl)-3-fluoro-benzonitrile 

Relevant academic research and scientific papers

PHENYLALKYL AND PYRIDYLALKYL PIPERAZINE DERIVATIVES

This invention relates to compounds of the formula (1) wherein R1, R3, R4, X1, and X2 are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other disorders.

Synthesis of further amino-halogen-substituted phenyl-aminoethanols

Starting from clenbuterol as a lead structure, new 4-amino-phenyl-aminoethanol analogues have been synthesized by different approaches. In these compounds one or both of the chlorine atoms of clenbuterol are replaced by other residues. This has led to compounds with high intrinsic β2-mimetic and/or β1-blocking activities. 1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-tert.-butylamino-ethanol hydrochloride (mabuterol) has been selected for clinical development. A detailed description is also given of the syntheses of new intermediate acetophenone derivatives as well as of the resolution of mabuterol into its enantiomers.