851179-01-6 Usage
General Description
3-Chloro-2,4-difluoropyridine is a chemical compound with the molecular formula C5H2ClF2N. It is a pyridine derivative that contains chlorine and fluorine atoms, and it is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 3-Chloro-2,4-difluoropyridine is known for its reactivity and is often used as a versatile intermediate in various chemical reactions. It is important to handle this compound with caution, as it can be harmful if ingested or inhaled, and should be stored and used in a well-ventilated area.
Check Digit Verification of cas no
The CAS Registry Mumber 851179-01-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,1,7 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 851179-01:
(8*8)+(7*5)+(6*1)+(5*1)+(4*7)+(3*9)+(2*0)+(1*1)=166
166 % 10 = 6
So 851179-01-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H2ClF2N/c6-4-3(7)1-2-9-5(4)8/h1-2H
851179-01-6Relevant articles and documents
Removal of fluorine from and introduction of fluorine into polyhalopyridines: An exercise in nucleophilic hetarenic substitution
Bobbio, Carla,Rausis, Thierry,Schlosser, Manfred
, p. 1903 - 1910 (2007/10/03)
Starting from six industrially available fluorinated pyridines, an expedient access to all three tetrafluoropyridines (2-4), all six trifluoropyridines (5-10), and the five non-commercial difluoropyridines (11-14 and 16) was developed. The methods employed for the selective removal of fluorine from polyfluoropyridines were the reduction by metals or complex hydrides and the site-selective replacement by hydrazine followed by dehydrogenation-dediazotation or dehydrochlorination-dediazotation. To introduce an extra fluorine atom, a suitable precursor was metalated and chlorinated before being subjected to a chlorine/ fluorine displacement process.