851179-03-8 Usage
Uses
Used in Pharmaceutical Industry:
3,4-Dichloro-2-fluoropyridine serves as a crucial intermediate in the production of pharmaceuticals. It is utilized for its reactivity and structural properties to facilitate the synthesis of a range of medicinal compounds, contributing to the development of new drugs and therapies.
Used in Agrochemical Industry:
In the agrochemical sector, 3,4-Dichloro-2-fluoropyridine is employed as an intermediate in the synthesis of various agrochemicals. Its role is pivotal in creating compounds that can be used in the development of pesticides, herbicides, and other agricultural products to enhance crop protection and yield.
Used in Organic Compounds Synthesis:
3,4-Dichloro-2-fluoropyridine also acts as a building block in the synthesis of a variety of heterocyclic compounds. Its unique structure and reactivity make it an essential component in the creation of complex organic molecules for diverse applications across different industries.
Safety and Handling:
Given the high reactivity and potential health and environmental hazards associated with 3,4-Dichloro-2-fluoropyridine, it is imperative that 3,4-Dichloro-2-fluoropyridine is handled and stored with extreme caution. Proper safety measures and protocols must be adhered to in order to mitigate any risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 851179-03-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,1,7 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 851179-03:
(8*8)+(7*5)+(6*1)+(5*1)+(4*7)+(3*9)+(2*0)+(1*3)=168
168 % 10 = 8
So 851179-03-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H2Cl2FN/c6-3-1-2-9-5(8)4(3)7/h1-2H
851179-03-8Relevant articles and documents
PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS
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Paragraph 0702-0704, (2020/01/04)
Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT 1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, and G, are defined herein.
Removal of fluorine from and introduction of fluorine into polyhalopyridines: An exercise in nucleophilic hetarenic substitution
Bobbio, Carla,Rausis, Thierry,Schlosser, Manfred
, p. 1903 - 1910 (2007/10/03)
Starting from six industrially available fluorinated pyridines, an expedient access to all three tetrafluoropyridines (2-4), all six trifluoropyridines (5-10), and the five non-commercial difluoropyridines (11-14 and 16) was developed. The methods employed for the selective removal of fluorine from polyfluoropyridines were the reduction by metals or complex hydrides and the site-selective replacement by hydrazine followed by dehydrogenation-dediazotation or dehydrochlorination-dediazotation. To introduce an extra fluorine atom, a suitable precursor was metalated and chlorinated before being subjected to a chlorine/ fluorine displacement process.
