851190-77-7

Basic information

• Product Name: 2-Propanol, 2-methyl-1-[(2-nitrophenyl)amino]-
• CAS NO: 851190-77-7
• Molecular Formula: C10H14N2O3
• Molecular Weight: 210.233
• Mol File: 851190-77-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Propanol, 2-methyl-1-[(2-nitrophenyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanol, 2-methyl-1-[(2-nitrophenyl)amino]-(851190-77-7)
• EPA Substance Registry System: 2-Propanol, 2-methyl-1-[(2-nitrophenyl)amino]-(851190-77-7)

Safety Data

• Hazardous Substances Data: 851190-77-7(Hazardous Substances Data)

Upstream product

• 2854-16-2 1-Amino-2-methyl-propan-2-ol 
• 88-73-3 2-Chloronitrobenzene 
• 1493-27-2 ortho-nitrofluorobenzene 
• 88-75-5 2-hydroxynitrobenzene 
• 344438-62-6 2-methyl-2-(2-nitrophenoxy)propionic acid ethyl ester 
• 64327-66-8 2-methyl-2-(2-nitrophenoxy)propionic acid chloride 
• 10514-62-2 2-Methyl-2-(2-nitrophenoxy)propanoic Acid 
• 140239-97-0 2-methyl-2-(2-nitrophenoxy)propionamide 

Relevant articles and documents

NEW BENZIMIDAZOLE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS

The present invention encompasses compounds of formula (I) (I), wherein the groups R1 to R5 have the meanings given in the claims and specification, their use as inhibitors of mutant EGFR, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.

Unexpected smiles rearrangement during borane reduction of 2-aryloxy-2-methylpropionamides

2-Nitrophenols spontaneously rearrange during alkylation with 2-bromo-2-methylpropionamide in the presence of cesium carbonate in acetonitrile to the corresponding 2-hydroxy-2-methyl-N-(2-nitrophenyl)propionamides. Upon reduction of 2-aryloxy-2-methylprop