64327-66-8

Upstream product

• 824-39-5 sodium o-nitrophenate 
• 88-75-5 2-hydroxynitrobenzene 
• 344438-62-6 2-methyl-2-(2-nitrophenoxy)propionic acid ethyl ester 
• 10514-62-2 2-Methyl-2-(2-nitrophenoxy)propanoic Acid 

Downstream Products

• 140239-97-0 2-methyl-2-(2-nitrophenoxy)propionamide 
• 851190-77-7 2-methyl-1-[(2-nitrophenyl)amino]propan-2-ol 
• 64327-64-6 1-Succinimido-3-methyl-3-(2-nitrophenoxy)butan-2-one 
• 64327-65-7 1-Bromo-3-methyl-3-(2-nitrophenoxy)butan-2-one 

Relevant academic research and scientific papers

Synthesis and biological evaluation of prodrugs for nitroreductase based 4-β-amino-4′-Demethylepipodophyllotoxin as potential anticancer agents

A series of prodrugs for nitroreductase (NTR) based 4-β-amino-4′- Demethylepipodophyllotoxin as potential anticancer agents were synthesized, and their antiproliferative activities in vitro showed compounds 2b (IC50 = 0.77, 0.83 and 1.19 μM) an

Unexpected smiles rearrangement during borane reduction of 2-aryloxy-2-methylpropionamides

2-Nitrophenols spontaneously rearrange during alkylation with 2-bromo-2-methylpropionamide in the presence of cesium carbonate in acetonitrile to the corresponding 2-hydroxy-2-methyl-N-(2-nitrophenyl)propionamides. Upon reduction of 2-aryloxy-2-methylprop