851193-98-1

Basic information

• Product Name: 4-cyano-5-ethyl-3-(4'-methoxy-biphenyl-4-yl)-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester
• CAS NO: 851193-98-1
• Molecular Weight: 388.466
• Mol File: 851193-98-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-cyano-5-ethyl-3-(4'-methoxy-biphenyl-4-yl)-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyano-5-ethyl-3-(4'-methoxy-biphenyl-4-yl)-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester(851193-98-1)
• EPA Substance Registry System: 4-cyano-5-ethyl-3-(4'-methoxy-biphenyl-4-yl)-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester(851193-98-1)

Safety Data

• Hazardous Substances Data: 851193-98-1(Hazardous Substances Data)

Upstream product

• 4397-53-9 p-benzyloxybenzaldehyde 
• 851193-89-0 4-cyano-5-ethyl-1-methyl-3-(4-trifluoromethanesulfonyloxy-phenyl)-1H-pyrrole-2-carboxylic acid ethyl ester 
• 5720-07-0 4-methoxyphenylboronic acid 
• 851193-71-0 3-(4-benzyloxy-phenyl)-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 851193-57-2 3-(4-benzyloxy-phenyl)-5-bromo-4-cyano-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 851193-72-1 4-cyano-5-ethyl-3-(4-hydroxyphenyl)-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 851192-88-6 3-(4-benzyloxy-phenyl)-4-cyano-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 851199-54-7 3-(4-benzyloxy-phenyl)-4-cyano-1H-pyrrole-2-carboxylic acid ethyl ester 

Relevant articles and documents

A novel class of positive allosteric modulators of AMPA receptors: Design, synthesis, and structure-activity relationships of 3-biphenyl-4-yl-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid, LY2059346

The synthesis and structure-activity relationship (SAR) of novel and highly potent positive allosteric modulators of AMPA receptors, 3-biphenyl-4-yl-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid, are described. These studies indicated that higher