851199-70-7 Usage
General Description
1-Imidazole-4-boronic ester is a chemical compound with the molecular formula C5H8BNO2. It is a boronic ester derivative of imidazole, a five-membered heterocyclic compound containing nitrogen. 1-iMidazole-4-boronic ester is commonly used in organic synthesis and medicinal chemistry as a reagent for the introduction of the imidazole group into various organic molecules. It can also be used as a building block for the synthesis of pharmaceuticals and other bioactive compounds. The boronic ester functional group in 1-imidazole-4-boronic ester makes it a valuable reagent for Suzuki-Miyaura cross-coupling reactions, which are widely used in the synthesis of complex organic molecules. Overall, 1-imidazole-4-boronic ester is an important and versatile chemical reagent in organic synthesis and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 851199-70-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,1,9 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 851199-70:
(8*8)+(7*5)+(6*1)+(5*1)+(4*9)+(3*9)+(2*7)+(1*0)=187
187 % 10 = 7
So 851199-70-7 is a valid CAS Registry Number.
851199-70-7Relevant articles and documents
Palladium-Catalyzed ipso-Borylation of Aryl Sulfides with Diborons
Bhanuchandra,Baralle, Alexandre,Otsuka, Shinya,Nogi, Keisuke,Yorimitsu, Hideki,Osuka, Atsuhiro
, p. 2966 - 2969 (2016/07/06)
A catalytic Miyaura-type ipso-borylation of aryl sulfides with diboron reagents has been achieved, providing arylboronate esters of synthetic use. The key conditions to transform inherently reluctant C-S bonds into C-B bonds include a palladium-NHC (N-heterocyclic carbene) precatalyst, bis(pinacolato)diboron, and lithium hexamethyldisilazide. This protocol is applicable to a reasonable range of aryl alkyl sulfides. Twofold borylation was observed in the reaction of diphenyl sulfide.
SULFONE AMIDE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE
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Paragraph 00251, (2015/07/23)
The present invention provides compounds of Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used medicaments.