851297-52-4

Upstream product

• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 107-11-9 1-amino-2-propene 

Downstream Products

• 305839-63-8 N-allyl-2-bromo-N-but-3-enyl-benzenesulfonamide 
• 1218787-92-8 N-allyl-N-2-methylallyl-2-bromobenzenesulfonamide 
• 1421639-50-0 1-phenyl-8-thia-9-azatricyclo[7.2.1.0^2,7]dodeca-2⁽⁷⁾,3,5,10-tetraene-8,8-dioxide 
• 1421639-47-5 1-(2-bromobenzenesulfonyl)-2,5-dihydro-1H-pyrrole-3-carboxylic acid methyl ester 
• 1421639-46-4 1-(2-bromophenylsulfonyl)-3-tert-butyl-2,5-dihydro-1H-pyrrole 
• 1421639-45-3 1-(2-bromophenylsulfonyl)-3-phenyl-2,5-dihydro-1H-pyrrole 
• 1218787-84-8 1-methyl-8-thia-9-azatricyclo[7.2.1.02,7]dodeca-2⁽⁷⁾,3,5,10-tetraene-8,8-dioxide 
• 1421639-28-2 C₁₁H₁₀BrNO₂S 
• 1421639-42-0 2-{[allyl-(2-bromobenzenesulfonyl)amino]methyl}acrylic acid methyl ester 
• 1421639-41-9 N-allyl-2-bromo-N-(3,3-dimethyl-2-methylenebutyl)benzenesulfonamide 
• 1421639-40-8 N-allyl-N-2-phenylallyl-(2-bromobenzene)sulfonamide 
• 1337570-34-9 2-{[(4S,5R)-4-benzyl-2-oxo-1,3-oxazolidin-5-yl]methyl}-2,3,4,5-tetrahydro-1H-1 λ6,2-benzothiazepine-1,1-dione 
• 1301767-82-7 tert-butyl N-[(1S,2R)-1-benzyl-3-(1,1-dioxo-1,3,4,5-tetrahydro-2H-1λ6,2-benzothiazepin-2-yl)-2-hydroxypropyl]carbamate 
• 1202207-20-2 C₁₇H₁₆N₂O₃S 

Relevant academic research and scientific papers

Regioselectivity in the intramolecular heck reaction of a series of cyclic sulfonamides: An experimental and computational study

Regioselectivity in the intramolecular Heck reaction of a series of N-sulfonyl-2,5-dihydro-3-substituted pyrroles was studied. These substrates are unbiased in terms of the formed ring size of the new heterocycle. Results indicate that high levels of regi

NRF2 REGULATORS

The present invention relates to bis aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.

Design, synthesis, and X-ray crystallographic analysis of a novel class of Hiv-1 protease inhibitors

In the present paper, design, synthesis, X-ray crystallographic analysis, and HIV-1 protease inhibitory activities of a novel class of compounds are disclosed. Compounds 28-30, 32, 35, and 40 were synthesized and found to be inhibitors of the HIV-1 protease. The crucial step in their synthesis involved an unusual endo radical cyclization process. Absolute stereochemistry of the three asymmetric centers in the above compounds have been established to be (4S,2′R,3′S) for optimal potency. X-ray crystallographic analysis has been used to determine the binding mode of the inhibitors to the HIV-1 protease.

Selective generation of quaternary all-carbon-centres through Heck-cyclisations: Synthesis of mesembrane

Described is an observation that the intramolecular Heck reaction of a trisubstituted alkene proceeds with high regioselectivity and leads to the preferential formation of a quaternary all-carbon-centre. This observation was subsequently applied in a short synthesis of (±)-mesembrane. The Royal Society of Chemistry 2010.

Synthesis of polycyclic lactams and sultams by a cascade ring-closure metathesis/isomerization and subsequent radical cyclization

Starting from readily available substrates, a new one-pot procedure has been devised to prepare polycyclic lactams and sultams. 2-Pyrrolines obtained from N,N-bisallylamides by ring-closure metathesis and subsequent isomerization promoted by ruthenium hyd