851334-65-1Relevant academic research and scientific papers
BICYCLIC COMPOUND
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Paragraph 1342; 1343; 1625; 1626, (2014/09/03)
The present invention provides a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
ACYL HYDRAZIDES AS KINASE INHIBITORS, IN PARTICULAR FOR SGK
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Page/Page column 43, (2010/11/24)
Novel acyl hydrazides of the formula (I), in which R1 - R9 have the meanings defined in claim 1, are SGK inhibitors and can be used for the treatment of SGK-induced diseases and conditions such as diabetes, obesity, metabolic syndrom
AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE
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Page/Page column 32, (2008/06/13)
The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5 and R6 is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7 is hydrogen or lower alkyl; R8 is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9 is -COR10, -A1-COR10, -O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, -OCH2-, etc, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.
