85137-57-1

Upstream product

• 90-01-7 salicylic alcohol 
• 288-13-1 NH-pyrazole 
• 704-65-4 2-(bromomethyl)phenyl acetate 
• 1120-82-7 pyrazole-1-methanol 
• 108-95-2 phenol 
• 603113-18-4 1-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzyl]-1H-pyrazole 

Downstream Products

• 1252590-69-4 2-((1H-pyrazol-1-yl)methyl)phenyl methanesulfonate 
• 1252590-68-3 2-((1H-pyrazol-1-yl)methyl)phenyl methanesulfonate 
• 1252590-67-2 2-((1H-pyrazol-1-yl)methyl)phenyl 4-methylbenzenesulfonate 
• 85128-04-7 1-Isopropylamino-3-(2-pyrazol-1-ylmethyl-phenoxy)-propan-2-ol 

Relevant academic research and scientific papers

Photo-Induced ortho-C-H Borylation of Arenes through in Situ Generation of Rhodium(II) Ate Complexes

Photoinduced in situ "oxidation"of half-sandwich metal complexes to "high-valent"cationic metal complexes has been used to accelerate catalytic reactions. Here, we report the unprecedented photoinduced in situ "reduction"of half-sandwich metal [Rh(III)] complexes to "low-valent"anionic metal [Rh(II)] ate complexes, which facilitate ligand exchange with electron-deficient elements (diboron). This strategy was realized by using a functionalized cyclopentadienyl (CpA3) Rh(III) catalyst we developed, which enabled the basic group-directed room temperature ortho-C-H borylation of arenes.

Microwave-Assisted Generation and Capture by Azoles of ortho-Quinone Methide Intermediates under Aqueous Conditions

An efficient activator-free protocol for the coupling of o-hydroxybenzyl alcohols and azoles in water has been developed. This C–N bond-formation process is supposed to proceed through an ortho-quinone methide intermediate. A broad range of o-hydroxybenzy

Direct synthesis of pyrazolo[5,1-a]isoindoles via intramolecular palladium-catalyzed C-H bond activation

An efficient, direct synthesis of pyrazolo-[5,1-a]isoindoles employing a palladium-catalyzed intramolecular C-H bond activation of 1-(2-halobenzyl) pyrazoles has been developed. The use of lithium chloride (LiCl) was found to be essential in these reactions, to suppress further C-H bond activation at the C-3 position of pyrazolo[5,1-a]isoindole, when C-3 is unsubstituted. This protocol can be applied to the synthesis of a pyrazolo[5,1-a]isoquinoline possessing a six-membered central ring system and a fully substituted pyrazolo[5,1-a]isoindole using sequential intra- and intermolecular C-H bond activation.

Antiarrhytmic benzylimidazole

Benzylazole derivatives being useful as antiarrhythmic agent are obtained by reacting the corresponding 2,3-epoxypropyloxybenzylazole with a primary or secondary amine.