851370-25-7

Upstream product

• 851370-24-6 2,2-Dimethyl-propionic acid (2R,3S)-4-[(R)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-trifluoromethanesulfonyloxy-6-triisopropylsilanyloxymethyl-5,6-dihydro-4H-pyran-3-yl]-2,3-dimethyl-butyl ester 
• 198411-17-5 1-((3-iodopropoxy)methyl)-4-methoxybenzene 
• 259540-48-2 (2R,3R)-1,4-bis[(4S)-4-(methylethyl)-2-oxo(1,3-oxazolidin-3-yl)]-2,3-dimethylbutane-1,4-dione 
• 5866-39-7 L(+)-tartaric acid 
• 127253-15-0 (2R,3R)-2,3-dimethyl-butane-1,4-diol 
• 851370-35-9 2,2-Dimethyl-propionic acid (2R,3S)-4-[(R)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-6-triisopropylsilanyloxymethyl-5,6-dihydro-4H-pyran-3-yl]-2,3-dimethyl-butyl ester 
• 851370-23-5 (R)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-one 
• 851370-21-3 2,2-Dimethyl-propionic acid (2R,3R)-4-iodo-2,3-dimethyl-butyl ester 
• 851370-34-8 2,2-Dimethyl-propionic acid (2R,3R)-4-hydroxy-2,3-dimethyl-butyl ester 
• 14289-62-4 1-(allyloxymethyl)-4-methoxybenzene 

Downstream Products

• 865446-74-8 Toluene-4-sulfonic acid (2R,3S)-4-{(R)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-[3-(4-methoxy-benzyloxy)-propyl]-6-[(E)-2-((S)-toluene-4-sulfinyl)-vinyl]-5,6-dihydro-4H-pyran-3-yl}-2,3-dimethyl-butyl ester 
• 851370-39-3 2,2-Dimethyl-propionic acid (2R,3S)-4-{(R)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-[3-(4-methoxy-benzyloxy)-propyl]-6-[(E)-2-((R)-toluene-4-sulfinyl)-vinyl]-5,6-dihydro-4H-pyran-3-yl}-2,3-dimethyl-butyl ester 
• 851370-20-2 2,2-Dimethyl-propionic acid (2R,3S)-4-{(R)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-[3-(4-methoxy-benzyloxy)-propyl]-6-[(E)-2-((S)-toluene-4-sulfinyl)-vinyl]-5,6-dihydro-4H-pyran-3-yl}-2,3-dimethyl-butyl ester 
• 865446-73-7 (2R,3S)-4-{(R)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-[3-(4-methoxy-benzyloxy)-propyl]-6-[(E)-2-((S)-toluene-4-sulfinyl)-vinyl]-5,6-dihydro-4H-pyran-3-yl}-2,3-dimethyl-butan-1-ol 
• 851370-27-9 2,2-Dimethyl-propionic acid (2R,3S)-4-{(1R,4R)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-hydroxy-1-[4-(4-methoxy-benzyloxy)-butyryl]-cyclohex-2-enyl}-2,3-dimethyl-butyl ester 
• 851370-30-4 Acetic acid (1R,4R)-4-((2S,3R)-4-azido-2,3-dimethyl-butyl)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-[4-(4-methoxy-benzyloxy)-butyryl]-cyclohex-2-enyl ester 
• 851370-36-0 2,2-Dimethyl-propionic acid (2R,3S)-4-{(S)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-formyl-2-[3-(4-methoxy-benzyloxy)-propyl]-5,6-dihydro-4H-pyran-3-yl}-2,3-dimethyl-butyl ester 
• 851370-40-6 1-[(1R,4R)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-4-hydroxy-1-((2S,3R)-4-hydroxy-2,3-dimethyl-butyl)-cyclohex-2-enyl]-4-(4-methoxy-benzyloxy)-butan-1-one 
• 851370-29-1 1-[(1R,4R)-1-((2S,3R)-4-Azido-2,3-dimethyl-butyl)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-hydroxy-cyclohex-2-enyl]-4-(4-methoxy-benzyloxy)-butan-1-one 

Relevant academic research and scientific papers

Synthesis of the A,G-spiroimine of pinnatoxins by a microwave-assisted tandem Claisen-Mislow-Evans rearrangement

The synthesis of the characteristic A,G-spiromine of pinnatoxins and pteriatoxins employing a microwave-assisted tandem Claisen-Mislow-Evans rearrangement is described. The study also features a highly efficient Suzuki-Miyaura cross-coupling reaction form

An approach to the imine ring system of pinnatoxins

(Chemical Equation Presented) A concise stereoselective approach to the spirobicyclic imine fragment of pinnatoxins and pteriatoxins is described. The approach relies on a tandem reaction sequence involving consecutive sigmatropic rearrangements to build