85143-89-1

Upstream product

• 85143-86-8 4-imidazol-1-yl-4-phenyl-but-3-en-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 70769-77-6 (Z)-4-Ethylsulfanyl-4-phenyl-but-3-en-2-one 
• 10348-80-8 3-Phenyl-3-phenoxy-but-3-en-2-on 
• 70769-78-7 (Z)-4-Phenyl-4-phenylsulfanyl-but-3-en-2-one 
• 85143-91-5 (Z)-4-Phenyl-4-propylamino-but-3-en-2-one 
• 50515-42-9 4-methoxy-4-phenyl-3-buten-2-one 
• 85143-92-6 (E)-4-Phenyl-4-pyrrolidin-1-yl-but-3-en-2-one 

Relevant academic research and scientific papers

The Reaction of 3-(1-Imidazolyl)-2-alken-1-ones with Nucleophiles

Generally 3-hetero-substituted 2-alken-1-ones were prepared from 1,3-alkanediones, 3-chloro-2-alken-1-ones, or conjugated ynones.The preparation of 3-hetero-substituted 2-alken-1-ones was subjected to some limitations by these methods.By the reaction of 3-(1-imidazolyl)-2-alken-1-ones (I) and 3-(3-oxo-1-alkenyl)-1-methylimidazolium iodides (II) with nucleophiles, 3-hetero-substituted 2-alken-1-ones could be obtained regioselectively in good yield under mild conditions.These results suggested that compounds I and II were concluded to be useful intermediates for the organic synthesis.