70769-77-6

Upstream product

• 85143-86-8 4-imidazol-1-yl-4-phenyl-but-3-en-2-one 
• 75-08-1 ethanethiol 
• 85143-89-1 1-Methyl-3-((E)-3-oxo-1-phenyl-but-1-enyl)-3H-imidazol-1-ium; iodide 
• 1817-57-8 4-phenyl-3-butyne-2-one 
• 81375-98-6 4,4-bis(ethylsulfanyl)but-3-en-2-one 
• 6783-05-7 trans-2-phenylvinylboronic acid 
• 98-80-6 phenylboronic acid 

Downstream Products

• 50515-42-9 4-methoxy-4-phenyl-3-buten-2-one 
• 93-91-4 1-phenylbutan-1,3-dione 
• 495-41-0 1-phenylbut-2-en-1-one 
• 2550-26-7 4-Phenyl-2-butanone 
• 70769-83-4 ethyl 3-hydroxy-1-phenylbutyl sulphide 
• 3729-90-6 3-methyl-1,5-diphenyl-1H-pyrazole 
• 73882-47-0 1-benzyl-3-methyl-5-phenyl-pyrazole 
• 80884-12-4 2-(3-Methyl-5-phenyl-pyrazol-1-yl)-pyridine 

Relevant academic research and scientific papers

Regio- and stereoselective synthesis of multisubstituted olefins and conjugate dienes by using α-oxo ketene dithioacetals as the building blocks

An efficient palladium(0)-catalyzed, Cu(I)-mediated synthetic route to trisubstituted olefins and conjugate dienes has been developed via oxo directing Liebeskind-Srogl cross-coupling reactions of gem-dihaloolefin-type α-oxo ketene dithioacetals with aryl

The Reaction of 3-(1-Imidazolyl)-2-alken-1-ones with Nucleophiles

Generally 3-hetero-substituted 2-alken-1-ones were prepared from 1,3-alkanediones, 3-chloro-2-alken-1-ones, or conjugated ynones.The preparation of 3-hetero-substituted 2-alken-1-ones was subjected to some limitations by these methods.By the reaction of 3-(1-imidazolyl)-2-alken-1-ones (I) and 3-(3-oxo-1-alkenyl)-1-methylimidazolium iodides (II) with nucleophiles, 3-hetero-substituted 2-alken-1-ones could be obtained regioselectively in good yield under mild conditions.These results suggested that compounds I and II were concluded to be useful intermediates for the organic synthesis.

Reduction of β-Arylthio- or β-Alkylthio-αβ-Unsaturated Ketones

The preparation and reduction of β-arylthio or β-alkylthio-αβ-unsaturated ketones (1) with lithium aluminium hydride or sodium borohydride have been examined.Reduction of the ketones (1) with lithium aluminium hydride gave αβ-unsaturated ketones (2), in which the olefinic (R1) and carbonyl (R2) substituents are reversed compared with the starting αβ-unsaturated ketone (1), or the saturated γ-hydroxy-sulphides (3).Reduction of the ketones (1) with sodium borohydride afforded only the αβ-unsaturated ketones (2).Reduction of (1) with sodium borohydride in the presence of metal halides gave the saturated ketones (5).