85155-28-8Relevant academic research and scientific papers
The Reaction of 3-(1-Imidazolyl)-2-alken-1-ones with Nucleophiles
Kashima, C.,Tajima, T.,Shimizu, M.,Omote, Y.
, p. 1325 - 1328 (2007/10/02)
Generally 3-hetero-substituted 2-alken-1-ones were prepared from 1,3-alkanediones, 3-chloro-2-alken-1-ones, or conjugated ynones.The preparation of 3-hetero-substituted 2-alken-1-ones was subjected to some limitations by these methods.By the reaction of 3-(1-imidazolyl)-2-alken-1-ones (I) and 3-(3-oxo-1-alkenyl)-1-methylimidazolium iodides (II) with nucleophiles, 3-hetero-substituted 2-alken-1-ones could be obtained regioselectively in good yield under mild conditions.These results suggested that compounds I and II were concluded to be useful intermediates for the organic synthesis.
