85160-87-8

Upstream product

• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 121-88-0 5-Nitro-2-aminophenol 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 

Downstream Products

• 105808-12-6 7-Isothiocyanato-2-phenyl-4H-benzo[1,4]oxazin-3-one 
• 105807-89-4 7-amino-2-phenyl-2H-1,4-benzoxazin-3(4H)-one 

Relevant academic research and scientific papers

FUSED RING COMPOUND HAVING UREA STRUCTURE

The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating / preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder. The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt: Formula (I) wherein A, B, R, R2 and R3 represent the same meanings as in the claims.

HETEROCYCLIC COMPOUND

The present invention provides a heterocyclic compound having an RORγt inhibitory action. The present invention relates to a compound represented by the formula (I): wherein Ar is a the partial structure (1) to the partial structure (5), Q is a bivalent group selected from the group consisting of (Ia)-(If), and B is a ring optinally having substituent(s), or a salt thereof.