851726-65-3

Basic information

• Product Name: 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one
• Synonyms: 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one;Benzyl 4-methyl-3-oxo-3,4-dihydropyrazine-1(2H)-carboxylate
• CAS NO: 851726-65-3
• Molecular Formula: C₁₃H₁₄N₂O₃
• Molecular Weight: 246.26186
• Mol File: 851726-65-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one(851726-65-3)
• EPA Substance Registry System: 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one(851726-65-3)

Safety Data

• Hazardous Substances Data: 851726-65-3(Hazardous Substances Data)

Usage

General Description

4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one is a chemical compound with a molecular formula C15H17N2O3. It is a heterocyclic compound that contains a pyrazine ring and a benzyloxycarbonyl group. 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one is commonly used in organic synthesis as a reagent for the protection of amines. It can also be used in the preparation of various pharmaceuticals and agrochemicals. The chemical properties and reactions of this compound make it valuable in the field of medicinal and agricultural chemistry.

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 851726-64-2 benzyl (2-((2,2-dimethoxyethyl)(methyl)amino)-2-oxoethyl)carbamate 

Downstream Products

• 59702-07-7 1-methylpiperazin-2-one 
• 870006-72-7 ethyl 8-(benzyloxy)-6-[(1,1-dioxido-1,2-thiazinan-2-yl)acetyl]-2-methyl-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylate 
• 870006-71-6 ethyl 6-(bromoacetyl)-8-(benzyloxy)-2-methyl-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylate 
• 869901-54-2 ethyl 6-acetyl-8-(benzyloxy)-2-methyl-1-oxo-1,2,3,4-tetrahydro-pyrrolo[1,2-a]-pyrazine-7-carboxylate 
• 870006-59-0 4-bromo-2-(4-fluorobenzyl)-5-(4-methyl-3-oxopiperazin-1-yl)pyridazin-3(2H)-one 
• 851726-92-6 ethyl 8-(benzyloxy)-6-bromo-2-methyl-1-oxo-1,2,3,4-tetrahydro-pyrrolo[1,2-a]-pyrazine-7-carboxylate 
• 851726-66-4 ethyl 8-(benzyloxy)-2-methyl-1-oxo-1,2,3,4-tetrahydro-pyrrolo[1,2-a]-pyrazine-7-carboxylate 

Relevant articles and documents

HIV INTEGRASE INHIBITORS

Substituted hydroxytetrahydropyrrolopyrazinone and substituted hydroxytetrahydro-pyrazolopyrazinone compounds of Formula (I) are inhibitors of HIV integrase and inhibitors of HIV replication: (I) wherein R1, R2, R3, R

HYDROXY PYRIDOPYRROLOPYRAZINE DIONE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS

Hydroxy-substituted pyridopyrrolopyrazine dione compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dione compounds are of Formula (I): (I) wherein a, b, A, B, R1, R2, R3, R4, R5, R6, R7 and R8 are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.