851726-65-3

Usage

Uses

Used in Organic Synthesis:
4-Benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one serves as a reagent for the protection of amines, a crucial step in the synthesis of various organic compounds. Its ability to shield amines from unwanted reactions allows for cleaner and more controlled synthetic pathways.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one is utilized as a key intermediate in the synthesis of drugs. Its unique structure and reactivity make it a valuable component in the creation of new medicinal agents with potential therapeutic benefits.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one is employed in the synthesis of pesticides and other crop protection agents. Its chemical properties enable the development of effective and targeted agrochemicals that can protect crops from pests and diseases while minimizing environmental impact.
Overall, 4-benzyloxycarbonyl-1-Methyl-3,4-dihydropyrazin-2(1H)-one is a versatile compound with significant applications across multiple industries, particularly in the fields of medicinal and agricultural chemistry, where its unique attributes contribute to the advancement of new and improved products.

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 851726-64-2 benzyl (2-((2,2-dimethoxyethyl)(methyl)amino)-2-oxoethyl)carbamate 

Downstream Products

• 59702-07-7 1-methylpiperazin-2-one 
• 870006-72-7 ethyl 8-(benzyloxy)-6-[(1,1-dioxido-1,2-thiazinan-2-yl)acetyl]-2-methyl-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylate 
• 870006-71-6 ethyl 6-(bromoacetyl)-8-(benzyloxy)-2-methyl-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylate 
• 869901-54-2 ethyl 6-acetyl-8-(benzyloxy)-2-methyl-1-oxo-1,2,3,4-tetrahydro-pyrrolo[1,2-a]-pyrazine-7-carboxylate 
• 870006-59-0 4-bromo-2-(4-fluorobenzyl)-5-(4-methyl-3-oxopiperazin-1-yl)pyridazin-3(2H)-one 
• 851726-92-6 ethyl 8-(benzyloxy)-6-bromo-2-methyl-1-oxo-1,2,3,4-tetrahydro-pyrrolo[1,2-a]-pyrazine-7-carboxylate 
• 851726-66-4 ethyl 8-(benzyloxy)-2-methyl-1-oxo-1,2,3,4-tetrahydro-pyrrolo[1,2-a]-pyrazine-7-carboxylate 

Relevant academic research and scientific papers

HIV INTEGRASE INHIBITORS

Substituted hydroxytetrahydropyrrolopyrazinone and substituted hydroxytetrahydro-pyrazolopyrazinone compounds of Formula (I) are inhibitors of HIV integrase and inhibitors of HIV replication: (I) wherein R1, R2, R3, R

HYDROXY PYRIDOPYRROLOPYRAZINE DIONE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS

Hydroxy-substituted pyridopyrrolopyrazine dione compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dione compounds are of Formula (I): (I) wherein a, b, A, B, R1, R2, R3, R4, R5, R6, R7 and R8 are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

HIV INTEGRASE INHIBITORS

Hydroxy-substituted pyrazinopyrrolopyridazine dione compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dione compounds are of Formula (I) wherein R1, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.