851729-28-7Relevant articles and documents
Synthesis and cytotoxicity of epoxide and pyrazole analogs of the combretastatins
LeBlanc, Regan,Dickson, John,Brown, Toni,Stewart, Michelle,Pati, Hari N.,VanDerveer, Don,Arman, Hadi,Harris, Jeff,Pennington, William,Holt Jr., Herman L.,Lee, Moses
, p. 6025 - 6034 (2007/10/03)
Twenty-six epoxide and corresponding pyrazole derivatives, of the structurally related chalcones and combretastatin A-4 (CA-4), were synthesized and tested for in vitro cytotoxicity. These molecules were synthesized by epoxidation of the relevant chalcone