85174-86-3Relevant academic research and scientific papers
Two Distinct Ag(I)- And Au(I)-Catalyzed Olefinations between α-Diazo Esters and N-Boc-Derived Imines
Kardile, Rahul Dadabhau,Liu, Rai-Shung
, p. 6452 - 6456 (2019)
Metal-catalyzed reactions between α-diazo esters and imines were well-known to yield aziridine derivatives exclusively. This work reports two new olefination reactions between N-Boc-derived (Boc = tert-Butyloxycarbonyl) imines and α-diazo esters with Ag(I) and Au(I) catalysts, respectively. Our mechanistic studies reveal that these new olefinations involve an initial attack of diazo esters on metal/imine complexes to form Mannich-addition intermediates, which subsequently afford α-aryl-β-aminoacrylates via a Roskamp reaction, or to form β-aryl-β-aminoacrylates via the formation of silver carbenes.
Substituent Dependence in the Synthesis of 2-Oxazolidinones from Phenyloxiranes, 2
Huth, Andreas,Frost, Elsbeth
, p. 261 - 266 (2007/10/02)
In the reaction with urea, the trans configurated glycidic esters 4a-d yield the predominantly new 5-aryl-2-oxooxazolidin-4-carboxylates 5 and 4-aryl-2-oxooxazolidin-5-carboxylates 6. 4,5-cis 5b, 4,5-cis 6b, 4,5-cis 6c, and 4,5-trans 6d have been isolated
