851745-19-2Relevant academic research and scientific papers
BENZODIAZEPINES AS HCV INHIBITORS
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Page/Page column 103-104, (2008/06/13)
The present invention relates to the use of benzodiazepines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates Io benzodiazepine compounds per se and their use as medicines. The present invention also concerns processes for the preparation of such compounds, pharmaceutical compositions comprising them, and combinations of said compounds with other anti-HCV agents.
11-Aryl-3,3-dimethyl-7- and 7,8-substituted 1,2,3,4,10,11-hexahydro-5H- dibenzo[b,e]-1,4-diazepin-1-ones
Tonkikh,Strakovs,Rizhanova,Petrova
, p. 949 - 955 (2007/10/03)
In reactions of 3-(5- and 5,6-substituted 2-aminophenylamino)-5,5- dimethylcyclohex-2-en-ones with carbaldehydes of pyridine, thiophene, and furan and substituted benzaldehydes, we have obtained 21 novel 7H-7-methoxycarbonyl-, 7-benzoyl-, 7-trifluoromethy
