851759-50-7Relevant academic research and scientific papers
Catalytic, asymmetric aza-Baylis-Hillman reaction of N-sulfonated imines with activated olefins by quinidine-derived chiral amines
Shi, Min,Xu, Yong-Mei,Shi, Yong-Ling
, p. 1794 - 1802 (2005)
The chiral nitrogen Lewis base, tricyclic cinchona alkaloid derivative TQO, is an effective promoter in the catalytic, asymmetric aza-Baylis-Hillman reaction of N-sulfonated imines Ar-CH=NR′ 1 (R′ = Ts, Ms, Ns, SES) with various activated olefins such as
Highly enantioselective aza-Baylis-Hillman reactions catalyzed by chiral thiourea derivatives
Raheem, Izzat T.,Jacobsen, Eric N.
, p. 1701 - 1708 (2007/10/03)
We report the discovery of asymmetric aza-Baylis-Hillman (ABH) reactions of N-p-nitrobenzenesulfonylimines with methyl acrylate catalyzed by chiral thiourea derivatives. A series of aromatic imines was found to undergo coupling with methyl acrylate with u
