851781-73-2Relevant academic research and scientific papers
Stereoselective synthesis of hex-2-(E)-en-4-yn-1,6-dioates and E,Z-muconic acid diesters via organo-catalyzed self-coupling of propiolates
Ramachandran, P. Veeraraghavan,Rudd, Michael T.,Reddy, M. Venkat Ram
, p. 2547 - 2549 (2005)
Alkyl propiolate couples with itself in the presence of catalytic DABCO under very mild conditions to provide a quantitative yield of E-hex-2-en-4-yne dioates. Hydrogenation of these enyne dioates using Lindlar catalyst provides the corresponding E,Z-diene dioate, a common structural motif found in an array of natural products.
