851853-06-0

Basic information

• Product Name: 3-Thiophenecarboxylic acid, 2-amino-4-(2-fluorophenyl)-5-(1-methylethyl)-, ethyl ester
• CAS NO: 851853-06-0
• Molecular Formula: C16H18FNO2S
• Molecular Weight: 307.389
• Mol File: 851853-06-0.mol

Chemical Properties

• CAS DataBase Reference: 3-Thiophenecarboxylic acid, 2-amino-4-(2-fluorophenyl)-5-(1-methylethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenecarboxylic acid, 2-amino-4-(2-fluorophenyl)-5-(1-methylethyl)-, ethyl ester(851853-06-0)
• EPA Substance Registry System: 3-Thiophenecarboxylic acid, 2-amino-4-(2-fluorophenyl)-5-(1-methylethyl)-, ethyl ester(851853-06-0)

Safety Data

• Hazardous Substances Data: 851853-06-0(Hazardous Substances Data)

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 626219-78-1 3-methyl-1-(2-fluorophenyl)butan-1-one 

Downstream Products

• 851853-37-7 [3-(3-fluorophenyl)-5-(2-fluorophenyl)-6-isopropyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-ylsulfanyl]-acetic acid ethyl ester 
• 851853-03-7 3-(3-fluoro-phenyl)-5-(2-fluoro-phenyl)-6-isopropyl-2-mercapto-3H-thieno[2,3-d]pyrimidin-4-one 

Relevant articles and documents

SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS

The present invention provides novel compounds and methods useful for treating transglutaminase associated disorders such as celiac spru, Alzheimer's disease and Huntington's disease. Certain compounds of the invention are tissue transglutaminase inhibito

Structure-activity relationship study of novel tissue transglutaminase inhibitors

Thieno[2,3-d]pyrimidin-4-one acylhydrazide derivatives were discovered as moderately potent inhibitors of TGase 2 (tissue transglutaminase) utilizing a fluorescence-based assay that measured TGase 2 catalyzed incorporation of the dansylated Lys derivative