626219-78-1

Basic information

• Product Name: 1-Butanone, 1-(2-fluorophenyl)-3-methyl-
• CAS NO: 626219-78-1
• Molecular Formula: C11H13FO
• Molecular Weight: 180.222
• Mol File: 626219-78-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 1-(2-fluorophenyl)-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1-(2-fluorophenyl)-3-methyl-(626219-78-1)
• EPA Substance Registry System: 1-Butanone, 1-(2-fluorophenyl)-3-methyl-(626219-78-1)

Safety Data

• Hazardous Substances Data: 626219-78-1(Hazardous Substances Data)

Usage

Type of Compound

Chemical compound

Use

Antifungal medication

Mechanism of Action

Inhibits the synthesis of ergosterol, a key component of fungal cell membranes

Forms Available

Oral and topical

Effectiveness

Generally well-tolerated and effective in treating fungal infections such as thrush, candidiasis, and ringworm.

Upstream product

• 394-47-8 2-fluorobenzonitrile 
• 926-62-5 isobutylmagnesium bromide 
• 765306-66-9 3-methyl-1-(2-fluorophenyl)butan-1-ol 

Downstream Products

• 851853-06-0 2-amino-4-(2-fluorophenyl)-5-isopropylthiophene-3-carboxylic acid ethyl ester 
• 765306-65-8 3-methyl-1-[2-(1-piperidinyl)phenyl]butoxime 
• 147769-96-8 3-methyl-1-[2-(piperidin-1-yl)phenyl]butan-1-imine 
• 108157-52-4 (S)-1-(2-piperidino-phenyl)-3-methyl-1-butylamine 
• 626219-81-6 C₂₀H₃₀N₂O₃ 
• 851753-84-9 3-methyl-1-(2-piperazin-1-yl-phenyl)-butan-1-one 
• 147770-03-4 3-methyl-1-(2-piperidin-1-yl-phenyl)-butan-1-one 
• 851853-37-7 [3-(3-fluorophenyl)-5-(2-fluorophenyl)-6-isopropyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-ylsulfanyl]-acetic acid ethyl ester 
• 851853-03-7 3-(3-fluoro-phenyl)-5-(2-fluoro-phenyl)-6-isopropyl-2-mercapto-3H-thieno[2,3-d]pyrimidin-4-one 

Relevant articles and documents

Preparation of 3-methyl-1 - [2 - (1-piperidinyl) phenyl] ding Yaan and the method of use of the product of

The invention discloses a method for preparing 3-methyl-1-(2-(1-piperidyl) phenyl) butyl imine and the application of the 3-methyl-1-(2-(1-piperidyl) phenyl) butyl imine. The yield of the 3-methyl-1-(2-(1-piperidyl) phenyl) butyl imine is 30 to 35 percent; the purity of the 3-methyl-1-(2-(1-piperidyl) phenyl) butyl imine is 99.0 to 99.5 percent (detected by an HPLC (high performance liquid chromatography) method); the 3-methyl-1-(2-(1-piperidyl) phenyl) butyl imine can be used as a standard substance for detecting impurities during the preparation of repaglinide amine, and can also be used for preparing high-purity repaglinide amine after subjected to catalytic hydrogenation or preparing 3-methyl-1-(2-(1-piperidyl) butanone after subjected to acidolysis; and the prepared 3-methyl-1-(2-(1-piperidyl) butanone can be used as raw material for synthesizing repaglinide amine or 3-methyl-1-(2-(1-piperidyl) phenyl) butyl imine, so as to be recycled, and raw material waste is avoided. The method is applicable to the synthesis of repaglinide amine.

LIGANDS OF MELANOCORTIN RECEPTORS AND COMPOSITIONS AND METHODS RELATED THERETO

Compounds which function as melanocortin receptor ligands and having utility in the treatment of melanocortin receptor-based disorders. The compounds have the following structure (I): (I) including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein m, n, q, s, R1, R1a, R1b, R2, R3, R4a, R4b, R5a, R5b, X1, X2, X3, X4 and Ar are as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.