851885-34-2Relevant academic research and scientific papers
Biochemical basis for differences in metabolism-dependent genotoxicity by two diazinylpiperazine-based 5-HT2C receptor agonists
Kalgutkar, Amit S.,Bauman, Jonathan N.,McClure, Kim F.,Aubrecht, Jiri,Cortina, Santo R.,Paralkar, Janvi
, p. 1559 - 1563 (2009)
The biochemical basis for S9-dependent mutagenic response of the 5-HT2C receptor agonist and diazinylpiperazine derivative 1 in the Salmonella Ames assay involves P450-mediated bioactivation to DNA-reactive quinone-methide, aldehyde and nitrone
PYRIDINE CARBOXYLIC ACID DERIVATIVES AS GLUCOKINASE MODULATORS
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Page/Page column 34, (2010/02/11)
A compound of Formula (I): wherein: A is phenyl or a 5- or 6-membered heteroaryl ring, optionally substituted; R1 and R2 are selected from hydrogen and methyl; with the proviso that at least one of R1 and R2 is
