851889-75-3

Upstream product

• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 652986-45-3 (3R,4R,5S)-4,6-[(R)-4-methoxy-benzylidenedioxy]-3,5-dimethyl-2-butanone 
• 444109-26-6 (3E,5S,6R,7S)-8-benzyloxy-6-(tert-butyldimethylsilanyloxy)-5,7-dimethyl-oct-3-enoic acid methyl ester 
• 444109-32-4 (3S,4R,5S,6Z)-1,1-dibromo-4-(tert-butyldimethylsilanyloxy)-3,5-trimethyl-7-trimethylsilanyl-octa-1,6-diene 
• 444109-27-7 (2S,3R,4S)-1-benzyloxy-3-(tert-butyldimethylsilanyloxy)-6,6-dibromo-2,4-dimethyl-hex-5-ene 
• 444109-23-3 (4S,5R,6S,7Z)-5-(tert-butyldimethylsilanyloxy)-4,6-dimethyl-8-trimethylsilanylnon-7-en-2-ynal 
• 444109-31-3 (2S,3R,4S,5Z)-3-(tert-butyldimethylsilanyloxy)-2,4-dimethyl-6-trimethylsilanyl-5-en-1-ol 
• 444109-43-7 (Z)-(2R,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-6-trimethylsilanyl-hept-5-enal 
• 184528-50-5 (E)-(5S,6R,7S)-8-Benzyloxy-6-hydroxy-5,7-dimethyl-oct-3-enoic acid methyl ester 
• 444109-24-4 (3E,5S,6S,7R)-6,8-dihydroxy-4,5,7-trimethyl-oct-3-enonic acid methyl ester 
• 444109-42-6 (2S,3R,4S)-5-benzyloxy-3-(tert-butyldimethylsilyloxy)-2,4-dimethyl-pentanal 
• 444109-29-9 (1E,3S,4R,5S)-6-benzyloxy-4-(tert-butyldimethylsilanyloxy)-3,5-dimethyl-1-iodo-1-trimethylsilanyl-hex-1-ene 
• 444109-30-2 (2Z,4S,5R,6S)-7-benzyloxy-5-(tert-butyldimethylsilanyloxy)-4,6-dimethyl-2-trimethylsilanyl-hept-2-ene 

Downstream Products

• 851889-77-5 (Z)-(2S,3S,5S,8S,9R,10S)-9-(tert-Butyl-dimethyl-silanyloxy)-2-[(2R,4R,5S)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-8,10-dimethyl-12-trimethylsilanyl-tridec-11-en-6-yne-3,5-diol 
• 851889-76-4 (2S,3R,4R,5S,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-3,5-[(R)-4-methoxybenzylidenedioxy]-1,7-dihydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn 
• 851889-88-8 (R)-2-[(2S,4S,5S,6S)-6-((3Z,8Z)-(2S,5S,6S,7S)-6-Hydroxy-9-iodo-2-methoxymethoxy-5,7-dimethyl-deca-3,8-dienyl)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionic acid methyl ester 
• 851889-66-2 (2R,3S,4S,5S,7S,8Z,10S,11S,12S,13Z)-14-iodo-3,5-[(S)-4-methoxybenzilidenedioxy]-7,11-bis-methoxymethoxy-2,4,10,12-tetramethylpentadeca-8,13-dienoic acid methyl ester 
• 851889-78-6 (R)-2-[(2S,4S,5S,6S)-6-[(Z)-(2S,5S,6R,7S)-6-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxy-5,7-dimethyl-9-trimethylsilanyl-dec-8-en-3-ynyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionaldehyde 
• 851889-82-2 (2R,3S,4S,5S,7S,8Z,10S,11S,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-14-iodo-3,5-[(S)-4-methoxybenzilidenedioxy]-7-methoxymethoxy-2,4,10,12-tetramethylpentadeca-8,13-dienoic acid methyl ester 
• 851889-79-7 (2R,3S,4S,5S,7S,10S,11S,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-3,5-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadeca-13-en-8-yn acid methyl ester 
• 851889-83-3 (R)-2-[(2S,4S,5S,6S)-6-[(3Z,8Z)-(2S,5S,6S,7S)-6-(tert-Butyl-dimethyl-silanyloxy)-2-methoxymethoxy-5,7-dimethyl-9-trimethylsilanyl-deca-3,8-dienyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionic acid methyl ester 
• 851889-80-0 (2R,3S,4S,5S,7S,10S,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-3,5-[(R)-4-methoxybenzylidenedioxy]-7-methoxymethoxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadeca-13-en-8-yn acid methyl ester 
• 851889-87-7 (R)-2-[(2S,4S,5S,6S)-6-((3Z,8Z,16Z)-(2S,5S,6S,7S,11S,12R,13S,14S,15S)-14-Carbamoyloxy-12-hydroxy-2,6-bis-methoxymethoxy-5,7,9,11,13,15-hexamethyl-nonadeca-3,8,16,18-tetraenyl)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionic acid methyl ester 
• 851889-86-6 (2R,3S,4S,5S,7S,8Z,10S,11S,12S,13Z,16S,17R,18S,19S,20S,21Z)-19-hydroxy-3,5-[(S)-4-methoxybenzilidenedioxy]-7,11-bis-methoxymethoxy-17-(4-methoxyphenoxyphenoxy)-2,4,10,12,14,16,18,20-octamethyltetracosa-8,13,21,23-tetraenoic acid methyl ester 
• 851889-65-1 2-[6-[14-carbamoyloxy-12-(4-methoxy-benzyloxy)-2,6-bis-methoxymethoxy-5,7,9,11,13,15-hexamethyl-nonadeca-3,8,16,18-tetraenyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionic acid methyl ester 
• 851889-85-5 2-[6-[12-(4-methoxy-benzyloxy)-2,6-bis-methoxymethoxy-5,7,9,11,13,15-hexamethyl-14-triethylsilanyloxy-nonadeca-3,8,16,18-tetraenyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Crotylsilane reagents in the synthesis of complex polyketide natural products: Total synthesis of (+)-discodermolide

An efficient, highly convergent stereocontrolled synthesis of (+)-discodermolide has been achieved with 2.1% overall yield (27 steps longest linear sequence). The absolute stereochemistry of the C1-C6 (12), C7-C14 (13), and C15-C24 (11) subunits was intro