851902-36-8Relevant academic research and scientific papers
Novel cyclopentane dicarboxamide sodium channel blockers as a potential treatment for chronic pain
Shao, Pengchang P.,Ok, Dong,Fisher, Michael H.,Garcia, Maria L.,Kaczorowski, Gregory J.,Li, Chunshi,Lyons, Kathryn A.,Martin, William J.,Meinke, Peter T.,Priest, Birgit T.,Smith, McHardy M.,Wyvratt, Matthew J.,Ye, Feng,Parsons, William H.
, p. 1901 - 1907 (2005)
A series of new voltage-gated sodium channel blockers were prepared based on the screening lead succinic diamide BPBTS. Replacement of the succinimide linker with the more rigid cyclic 1,2-trans-diamide linker was well tolerated. N-Methylation on the biph
