851961-99-4 Usage
Description
(2-pyridyldithio)-PEG2-alcohol is a PEG linker which contains a pyridyl disulfide moiety and an alcohol group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH level. The hydroxyl group allows for further derivatization of the compound. The hydrophilic PEG linker increases the water solubility of the compound.
Check Digit Verification of cas no
The CAS Registry Mumber 851961-99-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,9,6 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 851961-99:
(8*8)+(7*5)+(6*1)+(5*9)+(4*6)+(3*1)+(2*9)+(1*9)=204
204 % 10 = 4
So 851961-99-4 is a valid CAS Registry Number.
851961-99-4Relevant articles and documents
COMPOSITIONS AND METHODS FOR INDUCING IMMUNE TOLERANCE
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Paragraph 0328, (2019/01/08)
Several embodiments provided in the present disclosure relate to compositions that carry an antigen to which tolerance is desired, the antigen being coupled, bound, or otherwise joined to a targeting moiety, the targeting moiety configured to direct the composition to the liver of a subject. In several embodiments, the antigen in coupled to the targeting moiety by way of a polymeric linker. In several embodiments, the polymeric linker is configured to liberate the antigen in vivo. Methods of using the compositions to reduce and/or prevent unwanted immune responses against an antigen of interest are also provided.
