851975-10-5

Basic information

• Product Name: 2-METHYL-2-(1H-PYRAZOL-1-YL)PROPANOIC ACID
• Synonyms: 2-METHYL-2-(1H-PYRAZOL-1-YL)PROPANOIC ACID
• CAS NO: 851975-10-5
• Molecular Formula: C7H10N2O2
• Molecular Weight: 154.17
• Mol File: 851975-10-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 107-111°C
• Appearance: /
• CAS DataBase Reference: 2-METHYL-2-(1H-PYRAZOL-1-YL)PROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-2-(1H-PYRAZOL-1-YL)PROPANOIC ACID(851975-10-5)
• EPA Substance Registry System: 2-METHYL-2-(1H-PYRAZOL-1-YL)PROPANOIC ACID(851975-10-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 851975-10-5(Hazardous Substances Data)

Upstream product

• 288-13-1 NH-pyrazole 
• 2052-01-9 2-bromo-2-methylpropionic acid 

Downstream Products

• 1201657-32-0 ethyl 2-methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate 
• 1282514-64-0 ethyl 2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanoate 
• 1282513-03-4 2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanoic acid 
• 1282512-48-4 taselisib 
• 917569-72-3 2-(4-bromopyrazol-1-yl)-2-methylpropanoic acid 

Relevant articles and documents

Manufacture of the PI3K β-Sparing Inhibitor Taselisib. Part 2: Development of a Highly Efficient and Regioselective Late-Stage Process

A highly efficient and regioselective manufacturing route for the phosphoinositide 3-kinase β-sparing inhibitor taselisib was developed. Highlights of the synthesis include: (1) magnesium-mediated formation of a challenging cyclic amidine; (2) regioselect