851976-79-9Relevant academic research and scientific papers
Novel fluoropeptidomimetics: Synthesis, stability studies and protease inhibition
Annedi, Subhash C.,Majumder, Kanchana,Wei, Lianhu,Oyiliagu, Catherine E.,Samson, Sheeba,Kotra, Lakshmi P.
, p. 2943 - 2958 (2005)
Designer fluoropeptidomimetics as protease inhibitors are revealed. The key peptidomimetic region in the inhibitors contains a '-CHF-S-' moiety and is designed to mimic the tetrahedral oxyanion species during the hydrolysis of a peptide bond. Designed flu
