851980-78-4Relevant academic research and scientific papers
Azirine/oxindole ring enlargement via amidinium intermediates
Mekhael, Maged K. G.,Bienz, Stefan,Linden, Anthony,Heimgartner, Heinz
, p. 2385 - 2404 (2004)
A novel general method for the synthesis of oxindoles, namely the 'azirine/oxindole ring enlargement via amidinium-intermediates' has been established: the reaction of 2H-azirin-3-amines 1 with BF3· OEt2 in THF solution at -78° leads
