852049-59-3

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 850211-66-4 tert-Butyl-[(1R,2R,3S,4S)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-1-((S)-1-methyl-2-trityloxy-ethyl)-hex-5-enyloxy]-dimethyl-silane 
• 850211-62-0 (S)-4-Benzyl-3-[(2S,3R,4S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-5-trityloxy-pentanoyl]-oxazolidin-2-one 
• 850211-67-5 (2R,3R,4R,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4,6-trimethyl-7-trityloxy-heptanal 
• 850211-61-9 (S)-4-Benzyl-3-((2S,3R,4S)-3-hydroxy-2,4-dimethyl-5-trityloxy-pentanoyl)-oxazolidin-2-one 
• 850211-65-3 (3S,4S,5R,6R,7S)-6-(tert-Butyl-dimethyl-silanyloxy)-3,5,7-trimethyl-8-trityloxy-oct-1-en-4-ol 
• 398518-64-4 (2S,3R,4R,5S,6S,Z)-3-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6-trimethyldeca-7,9-dien-1-ol 
• 850211-63-1 (2R,3S,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-5-trityloxy-pentan-1-ol 
• 850211-64-2 (2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-5-trityloxy-pentanal 
• 850211-69-7 tert-Butyl-[(Z)-(1S,2R,3S,4S)-1-((R)-2-iodo-1-methyl-ethyl)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-octa-5,7-dienyloxy]-dimethyl-silane 
• 852049-58-2 (3R,4S,5S,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-((3Z,8Z)-(2S,5S,6S,7S)-9-iodo-2,6-bis-methoxymethoxy-5,7-dimethyl-deca-3,8-dienyl)-3,5-dimethyl-tetrahydro-pyran-2-one 

Relevant academic research and scientific papers

Total synthesis of (+)-discodermolide: A highly convergent fourth-generation approach

(Chemical Equation Presented) A highly convergent, fourth-generation total synthesis of (+)-discodermolide (1), with a longest linear sequence of 17 steps and an overall yield of 9.0%, has been achieved. Highlighting the strategy is the efficient construc