852142-49-5Relevant academic research and scientific papers
Facile generation method for conjugated allenyl esters based on retro-Dieckmann-type ring-opening reactions
Sano, Shigeki,Shimizu, Hisashi,Nagao, Yoshimitsu
, p. 2883 - 2886 (2005)
α-Alkynyl-α-ethoxycarbonyl cyclopentanones 1a-c and cyclohexanones 2a-c were readily synthesized by the reaction of ethyl 2-oxocyclopentanonecarboxylate 6 and ethyl 2-oxocyclohexanonecarboxylate 7 with alkynyllead triacetates 5a-c obtained from lithium acetylides 4a-c and lead tetraacetate. Treatment of 1a-c and 2a-c with 1 N KOH in THF or with n-Bu 4N+OEt- in EtOH and THF gave the corresponding conjugated allenyl esters 8a-c, 9a-c, 10a-c, and 11a-c in good to excellent yields, respectively.
