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2-fluoro-4-Methoxy-Benzenepropanoic acid, with the chemical formula C10H11FO3, is an organic compound that falls under the category of fluorobenzoic acid derivatives. It is characterized by its white to off-white powder form and has a molecular weight of 194.188 g/mol. 2-fluoro-4-Methoxy-Benzenepropanoic acid is recognized for its role as a building block in organic synthesis and is particularly valuable in pharmaceutical research for the synthesis of a variety of other compounds.
Used in Pharmaceutical Research:
2-fluoro-4-Methoxy-Benzenepropanoic acid is used as a key intermediate in the synthesis of pharmaceutical drugs, playing a crucial role in the development of new medications.
Used in Organic Synthesis:
In the field of organic synthesis, 2-fluoro-4-Methoxy-Benzenepropanoic acid is used as a building block for creating a range of different organic compounds, contributing to the diversity of chemical products.
Used in Medicinal Chemistry:
2-fluoro-4-Methoxy-Benzenepropanoic acid is utilized in medicinal chemistry for the development of novel pharmaceuticals, potentially leading to advancements in treatment options for various health conditions.
Given its specialized applications, the use of 2-fluoro-4-Methoxy-Benzenepropanoic acid is predominantly confined to research and development within the pharmaceutical and chemical industries, where its unique properties are harnessed to innovate and improve upon existing compounds and drug formulations.

852181-15-8

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852181-15-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 852181-15-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,1,8 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 852181-15:
(8*8)+(7*5)+(6*2)+(5*1)+(4*8)+(3*1)+(2*1)+(1*5)=158
158 % 10 = 8
So 852181-15-8 is a valid CAS Registry Number.

852181-15-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(2-Fluoro-4-methoxyphenyl)propanoic acid

1.2 Other means of identification

Product number -
Other names 2-Fluoro-4-methoxybenzenepropanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:852181-15-8 SDS

852181-15-8Relevant academic research and scientific papers

Synthesis method of succinic acid derivative or 3 -arylpropionic acid (by machine translation)

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Paragraph 0101-0114; 0115; 0138, (2020/10/30)

The invention discloses a synthesis method of a succinic acid derivative or 3 -arylpropionic acid, which comprises the following steps: adding a base in a drying reaction tube and CO removing CO. 2 The reaction is carried out under the irradiation of visible light, the reaction is carried out under visible light irradiation, and then separation and purification are carried out to obtain the butanedioic acid derivative or 3 -arylpropionic acid product; the base comprises sodium tert-butoxide, potassium tert-butoxide, lithium tert-butyl alcohol and 4 - potassium carbonate; and the reaction substrate comprises an acrylate compound or an aryl vinyl compound. CO can be induced by visible light. 2 The scheme provided by the invention is mild in reaction condition and wide in reaction 3 - substrate selectivity, and the reaction substrate is wide in selectivity, the raw materials are cheap and easily available, and the method has a good industrial application prospect. (by machine translation)

CYCLIC AMINE DERIVATIVE OR SALT THEREOF

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Page/Page column 25; 49, (2010/11/27)

Provided are compounds which are an NMDA antagonist having a broad safety margin and are useful as a treating agent or a preventing agent for Alzheimer's disease, cerebrovascular dementia, Parkinson's disease, ischemic apoplexy, pain, etc. Concretely prov

Chiral building blocks: Enantioselective syntheses of benzyloxymethyl phenyl propionic acids

Parsons, Jack G.,Stachurska-Buczek, Danuta,Choi, Neil,Griffiths, Peter G.,Huggins, Daniel A.,Krywult, Beata M.,Marino, Sharon T.,Nguyen, Thao,Sheehan, Craig S.,James, Ian W.,Bray, Andrew M.,White, Jonathan M.,Boyce, Rustum S.

, p. 449 - 458 (2007/10/03)

The synthesis of (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methoxyphenyl)- propionic acid, (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methylphenyl)propionic acid and (2S)-2-benzyl-oxymethyl-3-(2,4-dimethylphenyl)propionic acid has been achieved by TiCl4 mediated alkylation of the corresponding (4R)-4-benzyl-3-[3-(2-fluoro-4-methoxyphenyl-, 2-fluoro-4-methylphenyl-, 2,4-dimethylphenyl-)propionyl]-2-oxazolidinones, followed by hydrolysis of the chiral auxiliary. The stereochemistry of the alkylation reaction was confirmed by an X-ray crystal structure of (4R)-4-benzyl-3-[(2S)-2-benzyloxymethyl-3-(2- fluoro-4-methylphenyl)propionyl]-2-oxazolidinone.

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