852235-24-6Relevant academic research and scientific papers
Synthesis of α,β-unsaturated 4,5-disubstituted γ-lactones via ring-closing metathesis catalyzed by the first-generation Grubbs' catalyst
Bassetti, Mauro,D'Annibale, Andrea,Fanfoni, Alessia,Minissi, Franco
, p. 1805 - 1808 (2005)
(Chemical Equation Presented) 4-Methyl-5-alkyl-2(5H)-furanones have been prepared by ruthenium-catalyzed ring-closing metathesis of the suitable methallyl acrylates, Despite the electron deficiency of the conjugated double bond and of the gem-disubstitution of the allylic alkene moiety in the starting acrylates, the first-generation Grubbs' catalyst I proved to be an effective promoter for the ring closure, affording the expected butenolides in good to high yields.
