852238-11-0Relevant articles and documents
Synthesis of 1,2,3,12a,12b-hexahydrocyclopropa-[1,2-d]benzo[f]pyrrolo[1,2- b]isoquinolin-5,7-dione related to duocarmycins and anthramycin
Venkatram, Atigadda,Colley, Tara,DeRuiter, Jack,Smith, Forrest
, p. 297 - 301 (2007/10/03)
Structural features of the Duocarmycins and Anthramycin were incorporated into 1,2,3,12a,12b-hexa-hydro-cyclopropa[1,2-d]benzo[f]pyrrolo[1,2-b] isoquinolin-5,7-dione. The synthesis of the cis and trans diastereomers was accomplished using a benzyne Diels-