85225-54-3

Basic information

• Product Name: p-methoxydiphenylnitrone
• CAS NO: 85225-54-3
• Molecular Weight: 227.263
• Mol File: 85225-54-3.mol

Chemical Properties

• CAS DataBase Reference: p-methoxydiphenylnitrone(CAS DataBase Reference)
• NIST Chemistry Reference: p-methoxydiphenylnitrone(85225-54-3)
• EPA Substance Registry System: p-methoxydiphenylnitrone(85225-54-3)

Safety Data

• Hazardous Substances Data: 85225-54-3(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 100-65-2 N-Phenylhydroxylamine 
• 98-95-3 nitrobenzene 
• 836-41-9 p-methoxybenzylidene-phenylamine 

Downstream Products

• 87289-93-8 (3RS,4RS)-3-(4-methoxyphenyl)-2-phenyl-4-(phenylsulfonyl)isoxazolidine 
• 102972-07-6 (3R,3aR,6R,7S,7aS)-7-acetoxy-6-acetoxymethyl-3-p-methoxyphenyl-4-oxo-2-phenyl-tetrahydropyrano-<3,4-d>-isoxazolidine 
• 102972-07-6 (3S,3aR,6R,7S,7aS)-7-acetoxy-6-acetoxymethyl-3-p-methoxyphenyl-4-oxo-2-phenyl-tetrahydropyrano-<3,4-d>-isoxazolidine 
• 85225-59-8 3-(4-Methoxy-phenyl)-2-phenyl-isoxazolidine-5-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 142207-68-9 3RS-(3R^*,3aS^*,6aR^*)-2,3,6,6a-Tetrahydro-2-phenyl-3-(p-methoxyphenyl)-furo<3,4-d>isoxazol-4(3aH)-one 
• 142207-68-9 3RS-(3R^*,3aR^*,6aS^*)-2,3,6,6a-Tetrahydro-2-phenyl-3-(p-methoxyphenyl)-furo<3,4-d>isoxazol-4(3aH)-one 
• 103-82-2 phenylacetic acid 
• 836-41-9 p-methoxybenzylidene-phenylamine 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant articles and documents

One-pot synthesis of functionalized nitrones from nitro compounds

The zinc-mediated reduction of nitroalkanes and nitroarenes in the presence of aldehydes is an efficient method to synthesize a wide range of nitrones. This method is mild enough to accommodate a variety of functional groups. It is particularly useful when the intermediate hydroxylamines are unstable and/or water-soluble. We used it to prepare several aromatic, aliphatic and highly functionalized sugar-derived nitrones.

Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF3S-Containing Isoxazolidines

Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazolidines.

Controlling Asymmetric Remote and Cascade 1,3-Dipolar Cycloaddition Reactions by Organocatalysis

The regio- and stereoselective control of cycloaddition reactions to polyconjugated systems has been demonstrated by applying asymmetric organocatalysis. Reaction of 2,4-dienals with nitrones allows for a highly regio- and stereoselective 1,3-dipolar cycl

Regio-and stereoselective 1,3-dipolar cycloaddition of C-aryl-N- phenylnitrones over (E)-arylidene-(2H)-indan-1-ones: Synthesis of highly substituted novel spiro-isoxazolidines

Synthesis of a series of novel spiro-isoxazolidines has been accomplished in good yields by regio-and diastereoselective 1,3-dipolar cycloaddition of (E)-2-arylidene-(2H)-indan-1-ones 1a-d to C-aryl-N-phenylnitrones 2e-h. The structure of the spiro-adduct

Exploiting microwave-assisted neat procedures: synthesis of N-aryl and N-alkylnitrones and their cycloaddition en route for isoxazolidines

Microwave irradiation allows increasing the speed of several reactions and also offers the possibility of eliminating poisoning organic solvents. In this work we report the microwave-assisted neat synthesis of α-phenyl-tert-butylnitrone (PBN) and other alkyl and aryl nitrones and also the rapid synthesis of isoxazolidines resulting from 1,3-dipolar cycloaddition of nitrones to ethyl trans-crotonate.

1,3-Dipolar cycloadditions. Part-XIII: Microwave irradiation assisted synthesis and spectroscopic investigations of C-aryl-N-phenyl and C-aryl-N-(4′-chlorophenyl)nitrones

C-Aryl-N-phenylnitrones have been prepared in very high yields from N-phenylhydroxylamine and aryl aldehydes using the microwave irradiation technique within a few minutes. The synthesis of a new series of nitrones, viz. the series of C-aryl-N-(4′-chlorop

Investigations of regio- and stereoselectivities in the synthesis of cytotoxic isoxazolidines through 1,3-dipolar cycloadditions of nitrones to dipolarophiles bearing an allylic oxygen

Regio- and stereoselectivities in cycloadditions of nitrones to dipolarophiles bearing an allylic oxygen, which furnishes substituted-isoxazolidine analogs of the furanose ring of nucleosides, have been investigated. Although the obtained regioselectiviti

The cycloaddition of nitrones with homochiral cyclopropanes

(Chemical Equation Presented) The cycloaddition of nitrones and enantiomerically pure cyclopropane-1,1-dicarboxylates is examined. Transfer of optical activity to the adduct is dictated by thermal reaction conditions and nature of cyclopropane substitutio

Iron and manganese (III) - Porphyrins as new applicable catalysts for selective oxidation of imines with urea-hydrogen peroxide

A variety of imines were oxidised with urea-hydrogen peroxide using iron(III) and manganese (III)- tetraphenylporphyrins [Fe(TPP)Cl], [Mn(TPP)Cl] and manganese (III)-octabromotetraphenyl porphyrin [Mn(TPPBr8)Cl] as catalysts. Experimental resul

Synthesis of C, N-diaryl nitrones from the reduction of nitroarene with aromatic aldehydes promoted by metallic samarium

A mild and facile reduction of nitroarene with aromatic aldehydes promoted by metallic samarium to C, N-diaryl nitrones in moderate yields has been developed.