852292-42-3Relevant academic research and scientific papers
Catalytic Enantioselective Synthesis of Amino Skipped Diynes
Paioti, Paulo H. S.,Abboud, Khalil A.,Aponick, Aaron
, p. 2150 - 2153 (2016)
The Cu-catalyzed synthesis of nonracemic 3-amino skipped diynes via an enantiodetermining C-C bond formation is described using StackPhos as ligand. Despite challenging issues of reactivity and stereoselectivity inherent to these chiral skipped diynes, the reaction tolerates an extremely broad substrate scope with respect to all components and provides the title compounds in excellent enantiomeric excess. The alkyne moieties are demonstrated here to be useful synthetic handles, and 3-amino skipped diynes are convenient building blocks for enantioselective synthesis.
A new preparative route to substituted carbazoles by benzannulation
Serra, Stefano,Fuganti, Claudio
, p. 809 - 812 (2007/10/03)
A new regioselective pathway to substituted carbazole derivatives is described here. According to this procedure substituted 2-alkoxycarbonyl-4- acetoxy-9-(p-toluenesulfonyl) carbazoles are obtained by treatment of substituted 6-[2-(p-toluenesulfonyl-amin
