85231-94-3

Basic information

• Product Name: C₁₈H₂₈NO₅P
• Synonyms: C₁₈H₂₈NO₅P
• CAS NO: 85231-94-3
• Molecular Weight: 369.398
• Mol File: 85231-94-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₈NO₅P(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₈NO₅P(85231-94-3)
• EPA Substance Registry System: C₁₈H₂₈NO₅P(85231-94-3)

Safety Data

• Hazardous Substances Data: 85231-94-3(Hazardous Substances Data)

Upstream product

• 20039-33-2 diethoxyphosphoryl isocyanate 
• 85232-02-6 diethyl N-tert-butyloxycarbonylphosphoramidate 
• 104-54-1 3-Phenylpropenol 
• 85232-03-7 Diethyl N-sodio-N-(tert-butoxycarbonyl)phosphoramidate 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 
• 4392-24-9 Cinnamyl bromide 

Downstream Products

• 146287-09-4 Toluene-4-sulfonic acid; compound with (E)-3-phenyl-allylamine 
• 5586-89-0 3-phenylprop-2-en-1-amine hydrochloride 

Relevant articles and documents

New protocol for converting alcohols into amines

The reactions between diethyl N-(t-butoxycarbonyl)phosphoramidate 1, diisopropyl azodicarboxylate (DIAD), triphenylphosphine (TPP) and primary or secondary alcohols lead to the corresponding diethyl N-alkyl-N-(t-butoxycarbonyl)phosphoramidates 2a-o. Deprotection of crude 2 by refluxing with p-toluenesulfonic acid monohydrate in ethanol affords ammonium tosylates 3a-o in moderate to good overall yields. The N-alkylation of 1 proceeds stereoselectively with complete inversion of the configuration of the alkyl group.

Diethyl N-(t-Butoxycarbonyl)-phosphoramidate: A New, Useful Substitute of Phthalimide in Gabriel-Type Syntheses of Primary Amines

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