852330-72-4

Basic information

• Product Name: ((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamic acid 4-nitro-phenyl ester
• Synonyms: ((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamic acid 4-nitro-phenyl ester
• CAS NO: 852330-72-4
• Molecular Weight: 355.393
• Mol File: 852330-72-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamic acid 4-nitro-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamic acid 4-nitro-phenyl ester(852330-72-4)
• EPA Substance Registry System: ((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamic acid 4-nitro-phenyl ester(852330-72-4)

Safety Data

• Hazardous Substances Data: 852330-72-4(Hazardous Substances Data)

Upstream product

• 7693-46-1 4-Nitrophenyl chloroformate 
• 169749-99-9 (3S)-(-)-1-benzyl-3-(methylamino)pyrrolidine 

Downstream Products

• 762285-86-9 {(S)-1-[((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamoyl]-pyrrolidin-3-yl}-methyl-carbamic acid tert-butyl ester 
• 762285-42-7 {(S)-1-[((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamoyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester 

Relevant articles and documents

Bis(aminopyrrolidine)-derived ureas (APUs) as potent MCH1 receptor antagonists

Ureas derived from two substituted 3-aminopyrrolidine subunits were prepared as constrained analogs of a linear lead compound and tested as antagonists of the MCH1 receptor. The series was optimized for substitution and stereochemistry to generate a functional antagonist with a Ki of 3.3 nM and IC50 of 12 nM (GTPγS).