852333-36-9

Basic information

• Product Name: 5,6,7-trihydroxy-8-(morpholinomethyl)-2-phenyl-4H-chromen-4-one
• Synonyms: 5,6,7-trihydroxy-8-(morpholinomethyl)-2-phenyl-4H-chromen-4-one
• CAS NO: 852333-36-9
• Molecular Weight: 369.374
• Mol File: 852333-36-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5,6,7-trihydroxy-8-(morpholinomethyl)-2-phenyl-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7-trihydroxy-8-(morpholinomethyl)-2-phenyl-4H-chromen-4-one(852333-36-9)
• EPA Substance Registry System: 5,6,7-trihydroxy-8-(morpholinomethyl)-2-phenyl-4H-chromen-4-one(852333-36-9)

Safety Data

• Hazardous Substances Data: 852333-36-9(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 50-00-0 formaldehyd 
• 491-67-8 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one 
• 21967-41-9 baicalin 

Relevant articles and documents

Synthesis and structure confirmation of 7-ester-8-aminomethylene-substituted baicalein derivatives

Twelve baicalein derivatives, derivatized with 7-ester and 8-aminomethylene groups, were synthesized as cyclin-dependent kinase 1 (CDK1) inhibitors, by the addition of one of four secondary amines to C-8, using the Mannich reaction, followed by mono-esterification with one of three carboxylic acids. Analysis by 1H-, 13C-NMR, and HMBC spectra, as well as a chemical test, confirmed that the esterification occurred at the 7-phenolic hydroxyl position of baicalein but not at the 5- or 6-positions.

Baicalein or derivative thereof, preparation method and application of baicalein or derivative of baicalein

The invention discloses baicalein or a derivative thereof. The structure is shown in the specification, wherein R1 is hydrogen, alkyl, substituted or unsubstituted aryl; R2 is hydrogen, halogen, alkyl, alkoxy, substituted or unsubstituted amino, and subst

Flavonoid derivative as well as preparation method and identification method thereof

The invention discloses a flavonoid derivative, which has structure formulas shown as a general formula (I) and a general formula (II) as in the description, wherein R1 is alkyl or cyclo alkane; R2 isalkyl or cyclo alkane; R1, R2 and nitrogen atoms form cycloaliphatic ring or heterocycle; R3 is alkyl or aryl or aralkyl; the value of n is 1 to 10. The invention also discloses a preparation methodand an identification method of the flavonoid derivative.