85236-06-2Relevant academic research and scientific papers
12-S-CIS CONFORMATIONALLY LOCKED RETINOIDS: THERMAL AND PHOTOCHEMICAL INTERCONVERSIONS LEADING TO NEW GEOMETRIC ISOMERS
Chandraratna, Roshantha A. S.,Okamura, William H.
, p. 1003 - 1006 (2007/10/02)
For 12-s-cis locked retinal analogues, thermal equilibria are established between 11-cis,13-cis-1c and 13-cis-2c and between 9-cis,11-cis,13-cis-1d and 9-cis,13-cis-2d; a photoisomerisation occurs to transform 2c to all-trans-2a and 2d to 9-cis-2b.
12-s-Cis Conformationally Locked 11cis-Retinoids: A Delineation of the Thermal Requirements for -Sigmatropic Shifts and Electrocyclizations in the Vitamin A Series and Novel Spectral Properties
Chandraratna, Roshantha, A. S.,Bayerque, Ann L.,Okamura, William H.
, p. 3588 - 3594 (2007/10/02)
The thermally induced -sigmatropic rearrangement (69 deg C, 4 h) of the six-membered ring fused vinylallenol 5b, a process specific for preparing 11-cis-retinoids, afforded 24 (12percent) and the 12-s-cis-locked retinols 11-cis-7a (14percent), 11-cis
