85236-70-0

Upstream product

• 123-75-1 pyrrolidine 
• 99-31-0 5-aminoisophthalic acid 
• 99-27-4 dimethyl 5-aminoisophthalate 

Downstream Products

• 85236-71-1 3,5-bis<(N-pyrrolidinyl)methyl>benzenamine 
• 1579998-94-9 C₁₆H₁₉N₃O₃ 
• 1579999-12-4 (Z)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(3-((3,5-di(pyrrolidine-1-carbonyl)-phenyl)diazenyl)phenyl)thiourea 
• 1579999-13-5 (Z)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(3-((3,5-di(pyrrolidine-1-carbonyl)phenyl)-diazenyl)-5-(trifluoromethyl)phenyl)thiourea 
• 1579999-08-8 (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(3-((3,5-di(pyrrolidine-1-carbonyl)phenyl)-diazenyl)-5-(trifluoromethyl)phenyl)thiourea 
• 1579999-07-7 (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(3-((3,5-di(pyrrolidine-1-carbonyl)-phenyl)diazenyl)phenyl)thiourea 
• 1579999-01-1 (E)-(5-((3-amino-5-(trifluoromethyl)phenyl)diazenyl)-1,3-phenylene)bis(pyrrolidin-1-ylmethanone) 
• 1579999-00-0 (E)-(5-((3-aminophenyl)diazenyl)-1,3-phenylene)bis(pyrrolidin-1-ylmethanone) 
• 1579998-96-1 (E)-2-(3-((3,5-di(pyrrolidine-1-carbonyl)phenyl)diazenyl)-5-(trifluoromethyl)phenyl)-isoindoline-1,3-dione 
• 1579998-95-0 (E)-2-(3-((3,5-di(pyrrolidine-1-carbonyl)phenyl)diazenyl)phenyl)isoindoline-1,3-dione 
• 1312291-06-7 N-[3,5-bis(pyrrolidin-1-ylmethyl)phenyl]-7-chloroquinolin-4-amine 
• 1312291-07-8 N-{3,5-bis[(pyrrolidin-1-yl)carbonyl]phenyl}-7-chloroquinolin-4-amine 
• 85236-69-7 4-<3,5-bis<(N-pyrrolidinyl)methyl>anilino>-1-chlorophthalazine 

Relevant academic research and scientific papers

Photoswitchable thioureas for the external manipulation of catalytic activity

A series of azobenzene-based thiourea catalysts have been developed with the aim of achieving control over the catalytic activity by the use of light. The conceptual design of these systems relies on the inactivation by means of intramolecular hydrogen bonding, only likely to take place in one of their isomeric forms. After fine structure modulation of the catalyst a substantial difference in activity has been observed between the irradiated and the nonirradiated reaction. Furthermore, the system allowed in situ manipulation of the catalyst activity during the course of a given experiment.

7-CHLORO-QUINOLIN-4-AMINE COMPOUNDS AND USES THEREOF FOR THE PREVENTION OR TREATMENT OF DISEASES INVOLVING FORMATION OF AMYLOID PLAQUES AND/OR WHERE A DYSFUNCTION OF THE APP METABOLISM OCCURS

The present invention relates to compounds having the following Formula (I) for use in the prevention and/or the treatment of diseases involving formation of amyloid plaques and/or where a dysfunction of the APP metabolism occurs.

Synthesis and Antiarrhythmic and Parasympatholytic Properties of Substituted Phenols. 1. Heteroarylamine Derivatives

Twenty-four structural derivatives of the antiarrhythmic drug changrolin were synthesized and tested for antiarrhythmic and parasympatholytic activities.It was found that while the bis(pyrrolidinylmethyl)phenol pattern of changrolin appeared to be optimal