852360-83-9Relevant academic research and scientific papers
Sulfur-based protecting groups for pyrroles and the facile deprotection of 2-(2,4-dinitrobenzene)sulfinyl and sulfonyl pyrroles
Thompson, Alison,Butler, R. Jonathan,Grundy, Meaghan N.,Laltoo, Andrea B. E.,Robertson, Katherine N.,Cameron, T. Stanley
, p. 3753 - 3756 (2007/10/03)
(Chemical Equation Presented) The effectiveness of simple sulfinyl and sulfonyl groups as electron-withdrawing protecting groups for pyrroles has been analyzed using 13C NMR spectroscopy and confirmed by consideration of X-ray crystal structures. Additionally, the 2,4-dinitrobenzenesulfinyl and sulfonyl groups are shown to be effective electron-withdrawing protecting groups for pyrroles, and they can be removed by treatment with benzene thiol or thiolate under mild and specific conditions.
